14121-97-2

Basic information

• Product Name: Benzamide, 4-hydroxy-N-phenyl-
• CAS NO: 14121-97-2
• Molecular Formula: C13H11NO2
• Molecular Weight: 213.236
• Mol File: 14121-97-2.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: Benzamide, 4-hydroxy-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-hydroxy-N-phenyl-(14121-97-2)
• EPA Substance Registry System: Benzamide, 4-hydroxy-N-phenyl-(14121-97-2)

Safety Data

• Hazardous Substances Data: 14121-97-2(Hazardous Substances Data)

Upstream product

• 142-04-1 aniline hydrochloride 
• 100-09-4 4-methoxybenzoic acid 
• 81323-46-8 4-(Hydrazono-phenyl-methyl)-phenol 
• 7465-88-5 4-methoxy-N-phenylbenzamide 
• 611-94-9 4-Methoxybenzophenone 
• 782-45-6 4-amino-benzoic acid anilide 
• 3460-11-5 4-nitrobenzanilide 
• 103-71-9 phenyl isocyanate 
• 99-96-7 4-hydroxy-benzoic acid 
• 288-32-4 1H-imidazole 
• 79-37-8 oxalyl dichloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 591-50-4 iodobenzene 
• 619-57-8 p-hydroxybenzamide 

Downstream Products

• 124-38-9 carbon dioxide 
• 62-53-3 aniline 
• 108-95-2 phenol 
• 90446-66-5 2,6-bis(1-pyrrolidinylmethyl)-4-benzamidophenol 

Relevant articles and documents

Aryl alkyl ether compound as well as derivative, preparation method, pharmaceutical composition and application thereof

The invention discloses an aryl alkyl ether compound as well as a derivative, a preparation method, a pharmaceutical composition and application thereof. The structure of the aryl alkyl ether compound is shown as a formula (I). The aryl alkyl ether compound derivative relates to a stereoisomer, a tautomer, a metabolite, a metabolic precursor, a prodrug, a solvate, a salt of the solvate, a crystal, a pharmaceutically acceptable salt or a mixture of the stereoisomer, the tautomer, the metabolite, the metabolic precursor, the prodrug and the solvate of the aryl alkyl ether compound. The aryl alkyl ether compound and the derivative thereof have a remarkable inhibition effect on indoleamine 2, 3-dioxygenase 1, and can be used for preparing a medicine for treating indoleamine 2, 3-dioxygenase 1 mediated immunosuppression related diseases, and the prepared medicine can exert the medicine effect at the molecular level and is wide in application.

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The pivotal role of the myeloid ecotropic viral integration site 1 (MEIS1) transcriptional factor was reported in cardiac regeneration and hematopoietic stem-cell (HSC) regulation with our previous findings. MEIS1 as a promising target in the context of p

Chlorotropylium Promoted Conversions of Oximes to Amides and Nitriles

Chlorotropylium chloride as a catalyst for the transformations of oximes, ketones, and aldehydes to their corresponding amides and nitriles in excellent yields (up to 99 %) and in short reaction times (mostly 10–15 min). Oximes were electrophilically attacked on the hydroxyl oxygen by chlorotropylium. The produced tropylium oxime ethers were the key intermediates, of which the ketoxime ether led to amide through Beckmann rearrangement, and the aldoxime ether led to nitrile by nitrogen base DBU assisted formal dehydration. This chlorotropylium activation protocol offered general, mild, and efficient avenues bifurcately from oximes to both amides and nitriles by one organocatalyst.