1414860-35-7

Basic information

• Product Name: tert-butyl 3-oxa-6-aza-bicyclo[3.1.1]heptane-6-carboxylate
• Synonyms: tert-butyl 3-oxa-6-aza-bicyclo[3.1.1]heptane-6-carboxylate
• CAS NO: 1414860-35-7
• Molecular Weight: 199.25
• Mol File: 1414860-35-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 272.5±33.0 °C(Predicted)
• Density: 1.141±0.06 g/cm3(Predicted)
• CAS DataBase Reference: tert-butyl 3-oxa-6-aza-bicyclo[3.1.1]heptane-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-oxa-6-aza-bicyclo[3.1.1]heptane-6-carboxylate(1414860-35-7)
• EPA Substance Registry System: tert-butyl 3-oxa-6-aza-bicyclo[3.1.1]heptane-6-carboxylate(1414860-35-7)

Safety Data

• Hazardous Substances Data: 1414860-35-7(Hazardous Substances Data)

Upstream product

• 1016233-26-3 tert-butyl (2R,4S)-2,4-bis(hydroxymethyl)azetidine-1-carboxylate 
• 1414540-31-0 1-tert-butyl 2,4-diethyl cis-azetidine-1,2,4-tricarboxylate 
• 29548-85-4 2,4-dibromoglutaryl chloride 
• 174309-28-5 2,4-diethyl (2R,4S)-1-benzylazetidine-2,4-dicarboxylate 
• 870-78-0 2,4-dibromoglutaric acid diethyl ester 
• 2873-74-7 gloutaric dichloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Practical synthesis of 3-oxa-6-azabicyclo[31.1]heptane hydrotosylate; A novel morpholine-based building block

Bridged bicyclic morpholines are important building blocks in medicinal chemistry research. The bicyclic morpholine 3-oxa-6-azabicylo[3.1.1]heptane (3a) is of particular interest as a morpholine isostere because it is achiral and shows similar lipophilicity to that of morpholine, based on the cLogP of a derived analogue. The first synthesis of morpholine 3a (tosylate salt) is described; the seven-step sequence begins with inexpensive starting materials and uses straightforward chemistry. Georg Thieme Verlag Stuttgart ? New York.