141565-14-2

Basic information

• Product Name: (Z)-N-benzyl-α-methoxycarbonylmethanimine N-oxide
• CAS NO: 141565-14-2
• Molecular Weight: 193.202
• Mol File: 141565-14-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (Z)-N-benzyl-α-methoxycarbonylmethanimine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-N-benzyl-α-methoxycarbonylmethanimine N-oxide(141565-14-2)
• EPA Substance Registry System: (Z)-N-benzyl-α-methoxycarbonylmethanimine N-oxide(141565-14-2)

Safety Data

• Hazardous Substances Data: 141565-14-2(Hazardous Substances Data)

Upstream product

• 77486-09-0 (Z)-N-benzyl-α-methoxycarbonylmethanimine N-oxide 
• 53386-64-4 methyl 2-(benzylamino)acetate 
• 100-46-9 benzylamine 
• 109745-70-2 methyl glyoxylate methyl hemi-acetal 
• 29601-98-7 N-benzylhydroxylamine hydrochloride 
• 922-68-9 Methyl glyoxylate 
• 622-30-0 N-benzyl hydroxylalmine 

Downstream Products

• 77486-10-3 (E)-N-benzyl-α-methoxycarbonylmethanimine N-oxide 
• 342638-17-9 (1R,4R,5R)-4-[(S)-1-(tert-butyldimethylsilyloxy)ethyl]-2-phenylmethyl-3,7-dioxa-2-azabicyclo[3.3.0]octan-8-one 
• 1340600-95-4 C₁₄H₁₀⁽²⁾H₇NO₄ 
• 1340600-97-6 C₁₄H₁₆⁽²⁾HNO₄ 
• 1316673-94-5 N-benzylidene-1-(tert-butoxy)-2-methoxy-2-oxoethanamine N-oxide 

Relevant articles and documents

Dynamics in Catalytic Asymmetric Diastereoconvergent (3 + 2) Cycloadditions with Isomerizable Nitrones and α-Keto Ester Enolates

Reaction design in asymmetric catalysis has traditionally been predicated on a structurally robust scaffold in both substrates and catalysts, to reduce the number of possible diastereomeric transition states. Herein, we present the stereochemical dynamics in the Ni(II)-catalyzed diastereoconvergent (3 + 2) cycloadditions of isomerizable nitrile-conjugated nitrones with α-keto ester enolates. Even in the presence of multiple equilibrating species, the catalytic protocol displays a wide substrate scope to access a range of CN-containing building blocks bearing adjacent stereocenters with high enantio- and diastereoselectivities. Our computational investigations suggest that the enantioselectivity is governed in the deprotonation process to form (Z)-Ni-enolates, while the unique syn addition is mainly controlled by weak noncovalent bonding interactions between the nitrone and ligand.

Free-radical reaction of imine derivatives in water

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NOVEL E-Z EQUILIBRIUM OF N-ALKYL-α-ALKOXYCARBONYLNITRONE IN SOLUTION

Four N-alkyl-α-alkoxycarbonylnitrone were prepared and their NMR specra in C6D6, CDCl3, or CD3SOCD3 were measured.From the analyses of the spectra, it was found that the nitrones exhibited a facile equilibrium in all solvents used and E/Z ratio in equilibrium depended largely on the polarity of the solvent.