141694-63-5

Basic information

• Product Name: Benzene, [(2E)-3-iodo-2-propenyl]-
• CAS NO: 141694-63-5
• Molecular Formula: C9H9I
• Molecular Weight: 244.075
• Mol File: 141694-63-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, [(2E)-3-iodo-2-propenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(2E)-3-iodo-2-propenyl]-(141694-63-5)
• EPA Substance Registry System: Benzene, [(2E)-3-iodo-2-propenyl]-(141694-63-5)

Safety Data

• Hazardous Substances Data: 141694-63-5(Hazardous Substances Data)

Upstream product

• 51954-35-9 1,1-Diiod-2-phenylcyclopropan 
• 141694-60-2 1,1-diiodo-3-phenylpropane 
• 122-78-1 phenylacetaldehyde 
• 74-88-4 methyl iodide 
• 10147-11-2 propargyl benzene 
• 135983-67-4 cinnamyl alcohol 
• 3020-28-8 (iodomethyl)triphenylphosphonium iodide 
• 141694-57-7 Trifluoro-methanesulfonic acid 3-phenyl-1-trifluoromethanesulfonyloxy-propyl ester 
• 104-53-0 3-phenyl-propionaldehyde 

Downstream Products

• 37985-01-6 (E)-1-methoxy-4-(4-phenylbut-2-en-1-yl)benzene 
• 20067-98-5 trans-4-phenyl-2-butenenitrile 
• 18685-01-3 (E)-(3-chloroallyl)benzene 
• 868745-21-5 [(E)-(S)-1-Benzyl-3-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-allyl]-but-3-enyl-carbamic acid tert-butyl ester 
• 868745-20-4 [(E)-(S)-1-Benzyl-3-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-allyl]-but-3-enyl-amine 
• 920750-15-8 {2-[2-(2-isopropyl-5-methyl-cyclohexyl)-vinyl]-hept-6-enyl}-benzene 
• 922734-70-1 2,2-dimethyl-propionic acid 1-(2-isopropyl-5-methyl-cyclohexyl)-4-phenyl-but-2-enyl ester 
• 920750-14-7 {2-[2-(2-isopropyl-5-methyl-cyclohexyl)-vinyl]-hex-5-enyl}-benzene 
• 868744-81-4 (E)-(R)-1-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyl)-4-phenyl-but-2-en-1-ol 
• 127410-85-9 (E)-2-benzyl-1,3-decadiene 

Relevant articles and documents

Copper-catalyzed cross-coupling of amino acid-derived amides with (Z)-vinyl iodides: Unexpected solvent effect and preparation of plocabulin

A copper-catalyzed cross-coupling reaction of amino acid-derived amides and (Z)-vinyl iodide was studied to improve a key step in the synthesis of plocabulin, a novel microtubule destabilizer agent of marine origin. The study revealed a profound solvent effect with 1,2-dimethoxyethane (DME), which gave consistently high yields across a large variety of the amide and (Z)-vinyl iodide substrates. The protocol was successfully utilized in the preparation of plocabulin and provided a significantly improved yield.

Sterically biased 3,3-sigmatropic rearrangement of azides: Efficient preparation of nonracemic α-amino acids and heterocycles

(Chemical Equation Presented) Homochiral α-amino acids, heterocycles, and carbocycles are efficiently constructed via a short sequence of reactions starting from the chiral auxiliary p-menthane-3-carboxaldehyde. The key feature of the sequence is a highly selective tandem Mitsunobu/3,3-sigmatropic rearrangement of hydrazoic acid that procures enantiomerically enriched allylic azides. The sequence is either terminated by oxidative cleavage to provide amino acids or by ring-closing metathesis to provide heterocycles or carbocycles bearing nitrogen.

A new Procedure for the Synthesis of (E)-1-iodo-1-alkenes

(E)-1-iodo-1-alkenes 4 can be prepared stereoselectively from aldehydes 1 via IH-elimination of 1,1-di-iodoalkanes 3 with DBU. Key words: Vinyl iodide; diiodoalkane; elimination; stereoselectivity.