14172-52-2

Basic information

• Product Name: 1,3-Propanediol, 2-amino-1-[4-(methylthio)phenyl]-
• CAS NO: 14172-52-2
• Molecular Formula: C10H15NO2S
• Molecular Weight: 213.301
• Mol File: 14172-52-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-Propanediol, 2-amino-1-[4-(methylthio)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Propanediol, 2-amino-1-[4-(methylthio)phenyl]-(14172-52-2)
• EPA Substance Registry System: 1,3-Propanediol, 2-amino-1-[4-(methylthio)phenyl]-(14172-52-2)

Safety Data

• Hazardous Substances Data: 14172-52-2(Hazardous Substances Data)

Upstream product

• 135266-97-6 (2RS,3SR)-2-amino-3-hydroxy-3-(4-methylsulfanyl-phenyl)-propionic acid ethyl ester 
• 95448-24-1 (1S,2S)-threo-2-benzamido-1-(4-methylthiophenyl)-1,3-propanediol 
• 122934-50-3 (S)-(4-Methylsulfanyl-phenyl)-((S)-2-phenyl-4,5-dihydro-oxazol-4-yl)-methanol 
• 122934-50-3 (S)-(4-Methylsulfanyl-phenyl)-((S)-2-phenyl-4,5-dihydro-oxazol-4-yl)-methanol 
• 122934-51-4 (4-Methylsulfanyl-phenyl)-(2-phenyl-4,5-dihydro-oxazol-4-yl)-methanone 
• 16854-32-3 (1S,2S)-(+)-thiomicamine 
• 38423-42-6 N-[1-hydroxymethyl-2-(4-methylsulfanyl-phenyl)-2-oxo-ethyl]-acetamide 
• 23150-33-6 (1RS,2RS)-2-acetylamino-1-(4-methylsulfanyl-phenyl)-propane-1,3-diol 

Downstream Products

• 4302-89-0 (1RS,2RS)-2-(2,2-dichloro-acetylamino)-1-(4-methylsulfanyl-phenyl)-propane-1,3-diol 
• 129025-52-1 D-4-HYDROXYMETHYL-5-[4-(METHYLMERCAPTO)PHENYL]-2-(4-NITROPHENYL)-2-OXAZOLINE 
• 126429-07-0 D-(-)-threo-2-phenyl-4-hydroxymethyl-5-(4-methylthiophenyl)-2-oxazoline 
• 19934-71-5 2,2-dichloro-N-{1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide 
• 4302-89-0 (1R,2R)-2-(2,2-dichloro-acetylamino)-1-(4-methylsulfanyl-phenyl)-propane-1,3-diol 
• 71830-03-0 (1S,2S)-2-(2,2-dichloro-acetylamino)-1-(4-methylsulfanyl-phenyl)-propane-1,3-diol 
• 51458-28-7 (1R,2R)-2-amino-1-<4-(methylsulphonyl)phenyl>-1,3-propanediol 
• 15318-45-3 thiamphenicol 
• 122934-50-3 (R)-(4-Methylsulfanyl-phenyl)-((S)-2-phenyl-4,5-dihydro-oxazol-4-yl)-methanol 
• 23150-35-8 (R*,R*)-(+)-thiomicamine 
• 16854-32-3 (1S,2S)-(+)-thiomicamine 

Relevant articles and documents

Micro-reaction system and method for continuously preparing 2-amino-1,3-diol compounds

The invention belongs to the technical field of pharmaceutical engineering, and particularly relates to a micro-reaction system and method for continuously preparing 2-amino-1,3-diol compounds. The micro-reaction system comprises a micro-mixer and a micro-channel reactor which communicate with each other in sequence; the micro-mixer is used for mixing a solution of a raw material 2-nitro-1,3-diol compound with hydrogen; and the micro-channel reactor is used for continuous reaction of the mixture. The method comprises the following steps: packing a palladium catalyst in the microchannel reactor, dissolving a 2-nitro-1,3-diol compound in an organic solvent, conveying the dissolved 2-nitro-1,3-diol compound and hydrogen into the microchannel reactor at the same time, and carrying out a continuous catalytic hydrogenation reaction to obtain the corresponding 2-amino-1, 3-diol compound. According to the method, the reaction time is only several minutes, the yield of the product 2-amino-1,3-diol compound is larger than 99%, the technological process is continuous, the automation degree is high, the space time yield is high, operation is easy and convenient, the step of separating reaction liquid from a catalyst is not needed, cost is low, and the method is environmentally friendly, safe and easy for industrial production.