1418203-73-2Relevant articles and documents
Design, synthesis and in vitro evaluation of a series of α-substituted phenylpropanoic acid PPARγ agonists to further investigate the stereochemistry-activity relationship
Ohashi, Masao,Nobusada, Hiromi,Matsuno, Kenji,Miyachi, Hiroyuki,Nakagome, Izumi,Hirono, Shuichi,Kasuga, Jun-Ichi,Hashimoto, Yuichi,Makishima, Makoto
, p. 6375 - 6383,9 (2012/12/12)
We previously demonstrated that the α-benzylphenylpropanoic acid-type PPARγ-selective agonist 6 exhibited a reversed stereochemistry-activity relationship, that is, the (R)-enantiomer is a more potent PPARγ agonist than the (S)-enantiomer, compared with s