143060-05-3

Basic information

• Product Name: (E)-3-[(2S,4S,5R)-3-(2-Iodo-acetyl)-4-methyl-5-phenyl-oxazolidin-2-yl]-acrylic acid methyl ester
• Synonyms: (E)-3-[(2S,4S,5R)-3-(2-Iodo-acetyl)-4-methyl-5-phenyl-oxazolidin-2-yl]-acrylic acid methyl ester
• CAS NO: 143060-05-3
• Molecular Weight: 415.228
• Mol File: 143060-05-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-3-[(2S,4S,5R)-3-(2-Iodo-acetyl)-4-methyl-5-phenyl-oxazolidin-2-yl]-acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-[(2S,4S,5R)-3-(2-Iodo-acetyl)-4-methyl-5-phenyl-oxazolidin-2-yl]-acrylic acid methyl ester(143060-05-3)
• EPA Substance Registry System: (E)-3-[(2S,4S,5R)-3-(2-Iodo-acetyl)-4-methyl-5-phenyl-oxazolidin-2-yl]-acrylic acid methyl ester(143060-05-3)

Safety Data

• Hazardous Substances Data: 143060-05-3(Hazardous Substances Data)

Upstream product

• 16251-50-6 (1S,2R)-(+)-2-chloro-N-(2-hydroxy-1-methyl-2-phenylethyl)acetamide 
• 32815-00-2 monofumaraldehyde dimethylacetal monomethylester 
• 492-41-1 (1R,2S)-norephedrine 
• 143060-10-0 (E)-3-[(2S,4S,5R)-3-(2-Chloro-acetyl)-4-methyl-5-phenyl-oxazolidin-2-yl]-acrylic acid methyl ester 

Downstream Products

• 137314-91-1 (2R,3S,6R,7R,7aS)-3,6,7-Trimethyl-2-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one 

Relevant articles and documents

Stereoselective Radical-Mediated Cyclization of Norephedrine Derived α-Iodoamides: Synthesis of Enantiopure Pyrrolidines and Transition State Modelling

Radical-mediated cyclization of norephedrine derived α-iodoamides 1 was found to be highly stereoselective ( 97:3) favouring diastereoisomer 2.Bicyclic lactams 2 were transformed in high yields into enantiomerically pure pyrrolidines 10.Transition stat