1435943-40-0

Basic information

• Product Name: methyl 5-cyano-6-(4-fluorophenyl)-2-hydroxy-4-phenyl-3,4-dihydro-2H-pyran-2-carboxylate
• Synonyms: methyl 5-cyano-6-(4-fluorophenyl)-2-hydroxy-4-phenyl-3,4-dihydro-2H-pyran-2-carboxylate
• CAS NO: 1435943-40-0
• Molecular Weight: 353.35
• Mol File: 1435943-40-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 5-cyano-6-(4-fluorophenyl)-2-hydroxy-4-phenyl-3,4-dihydro-2H-pyran-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-cyano-6-(4-fluorophenyl)-2-hydroxy-4-phenyl-3,4-dihydro-2H-pyran-2-carboxylate(1435943-40-0)
• EPA Substance Registry System: methyl 5-cyano-6-(4-fluorophenyl)-2-hydroxy-4-phenyl-3,4-dihydro-2H-pyran-2-carboxylate(1435943-40-0)

Safety Data

• Hazardous Substances Data: 1435943-40-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 4640-67-9 3-(4-fluorophenyl)-3-oxopropionitrile 
• 107969-78-8 methyl benzylidenepyruvate 
• 1125-88-8 benzaldehyde dimethyl acetal 

Relevant articles and documents

Efficient enantioselective synthesis of dihydropyrans using a chiral N, N ′-dioxide as organocatalyst

The bifunctional organocatalyst C3 N,N′-dioxide has been successfully applied to the asymmetric cascade Michael/hemiacetalization reaction of α-substituted cyano ketones and β,γ-unsaturated α-ketoesters for the synthesis of multifunctionalized chiral dihydropyrans. The corresponding products were obtained in excellent yields (up to 99%) with high to excellent enantioselectivities (up to 99% ee).