1438279-61-8Relevant articles and documents
Access to trans-3,4-Dihydroxy-2-alkylpyrrolidines and piperidines by use of stereodefined cyclic N,O-Acetals as a Diversity-generating element
Kang, Soyeong,Kim, Dong-Gil,Rhee, Young Ho
, p. 16391 - 16396 (2014)
A highly efficient and stereoselective synthetic pathway towards trans-3,4-dihydroxy-2-alkylpyrrolidines and piperidines is described. The nature of the protecting groups on the hydroxyl moieties played a crucial role on the trans selectivity. By using this method, a concise total synthesis of (-)-2-epilentiginosine has been achieved.
Synthetic strategy for cyclic amines: A stereodefined cyclic N,O-acetal as a stereocontrol and diversity-generating element
Kim, Haejin,Lim, Wontaeck,Im, Donghong,Kim, Dong-Gil,Rhee, Young Ho
supporting information, p. 12055 - 12058 (2013/01/16)
In control: A new synthetic strategy towards cyclic amines was developed and exploits a stereodefined cyclic N,O-acetal as the key stereocontrol and diversity-generating element. The cyclic N,O-acetal was prepared from the sequential asymmetric hydroamina