143885-75-0

Basic information

• Product Name: 2-Propen-1-one,1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-methoxyphenyl)-,(2E)-
• Synonyms: 2-Propen-1-one,1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-methoxyphenyl)-,(E)-; Glychalcone A
• CAS NO: 143885-75-0
• Molecular Formula: C22H22 O5
• Molecular Weight: 366.414
• Mol File: 143885-75-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one,1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-methoxyphenyl)-,(2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one,1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-methoxyphenyl)-,(2E)-(143885-75-0)
• EPA Substance Registry System: 2-Propen-1-one,1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-methoxyphenyl)-,(2E)-(143885-75-0)

Safety Data

• Hazardous Substances Data: 143885-75-0(Hazardous Substances Data)

Upstream product

• 404597-94-0 1-(2-methoxy-4,6-bis(methoxymethoxy)phenyl)ethan-1-one 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 450336-13-7 1-(2,6-dihydroxy-4-(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)ethanone 
• 450336-14-8 1-(2-hydroxy-6-methoxy-4-(methoxymethoxy)-3-(3-methylbut-2-enyl)phenyl)ethanone 
• 30403-01-1 1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]ethanone 
• 65490-09-7 2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone 
• 3602-54-8 4,6-dihydroxy-2-methoxyacetophenone 
• 541-47-9 3-Methylbutenoic acid 
• 1019-60-9 2,3-dihydro-5-hydroxy-7-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one 
• 883-09-0 5,7-dihydroxy-2,2-dimethylchroman-4-one 
• 108-73-6 3,5-dihydroxyphenol 
• 25983-76-0 isoevodionol 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1034927-75-7 5-[(-)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy-methoxy]-2-(4-methoxyphenyl)-8,8-dimethyl-2,3-dihydro-8H-pyrano[2,3-f]chromen-4-one 
• 1034927-74-6 5-hydroxy-2-(4-methoxyphenyl)-8,8-dimethyl-2,3-dihydro-8H-pyrano[2,3-f]chromen-4-one 
• 450336-11-5 (+/-)-5-methoxy-2-(4-methoxyphenyl)-8,8-dimethyl-2,3-dihydro-8H-pyrano[2,3-f]chromen-4-one 

Relevant articles and documents

An efficient and rapid synthetic route to biologically interesting pyranochalcone natural products

An efficient and concise total synthesis of naturally occurring pyranochalcones was achieved from readily available 2,4-dihydroxyacetophenone and 2,4-dihydroxy-6-methoxyacetophenone. The key steps in the synthetic strategy were ethylenediamine diacetate-c

Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders

The present invention relates to certain chromane-like cyclic prenylflavonoids, in particular the compounds of formulae (I), (II) and (III) as described and defined herein, for use in the treatment or prevention of a neurological disorder, as well as their use in promoting neuronal differentiation, neurite outgrowth and neuroprotection.

First total synthesis of (±)-glyflavanone-A

First convergent synthesis (±)-glyflavanone-A (1), a novel pyranoflavanone natural product, starting from phloroacetophenone and p-anisaldehyde is described.