144148-78-7

Basic information

• Product Name: ethyl (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenoate
• Synonyms: ethyl (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenoate
• CAS NO: 144148-78-7
• Molecular Weight: 460.592
• Mol File: 144148-78-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenoate(144148-78-7)
• EPA Substance Registry System: ethyl (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenoate(144148-78-7)

Safety Data

• Hazardous Substances Data: 144148-78-7(Hazardous Substances Data)

Upstream product

• 144147-77-3 6-(4-tert-butylbenzyl)-2-(2,2-dimethoxyacetyl)cyclohexanone 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 144148-22-1 7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazole-3-carboxaldehyde 

Downstream Products

• 153124-87-9 (E)-7-[7-(4-tert-Butyl-benzyl)-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-5-hydroxy-3-oxo-hept-6-enoic acid ethyl ester 
• 144149-44-0 (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenal 
• 144149-10-0 (E)-3-<7-(4-tert-butylbenzyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl>-2-propenol 

Relevant articles and documents

HMG-CoA Reductase Inhibitors: Design, Synthesis, and Biological Activity of Tetrahydroindazole-Substituted 3,5-Dihydroxy-6-heptenoic Acid Sodium Salts

Compounds comprising a series of 7--3,5-dihydroxy-6-heptenoic acid sodium salts (18) were synthesized and tested for their ability to inhibit HMG-CoA reductase in a partially purified enzyme preparati