144171-61-9

Basic information

• Product Name: Indoxacarb
• Synonyms: INDOXACARB;INDOXACARB-MP;METHYL 7-CHLORO-2,5-DIHYDRO-2-[N-(METHOXYCARBONYL)-4-(TRIFLUOROMETHOXY)ANILINOCARBONYL]INDENO[1,2-E][1,3,4]OXADIAZINE-4A(3H)CARBOXYLATE;7-Chloro-2,5-dihydro-2-(((methoxycarbonyl)(4-(trifluoromethoxy)phenyl)amino)carbonyl)-indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid methyl ester;indeno[1,2-e][1,3,4}oxadiazine-4a(3h)carboxylic;indeno[1,2-e][1,3,4}oxadiazine-4a(3h)carboxylicacid,7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(t;indeno[1,2-e][1,3,4}oxadiazine-4a(3h)carboxylicacid,7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoro-methoxy)phenyl]amin;Carprofen, Vetranal
• CAS NO: 144171-61-9
• Molecular Formula: C22H17ClF3N3O7
• Molecular Weight: 527.83
• Mol File: 144171-61-9.mol
• Article Data: 9

Chemical Properties

• Melting Point: 139-141℃
• Boiling Point: 571.4 °C at 760 mmHg
• Flash Point: 299.3 °C
• Appearance: /
• Density: 1.53
• Vapor Pressure: 4.59E-13mmHg at 25°C
• Refractive Index: 1.601
• PKA: -1.75±0.40(Predicted)
• CAS DataBase Reference: Indoxacarb(CAS DataBase Reference)
• NIST Chemistry Reference: Indoxacarb(144171-61-9)
• EPA Substance Registry System: Indoxacarb(144171-61-9)

Safety Data

• Hazard Codes: Xn;N,N,Xn,T
• Statements: 22-36-43-50/53-57-48/25-20/22
• Safety Statements: 26-36/37-60-61-45-37-24
• RIDADR: UN 3077
• WGK Germany: 3
• Hazardous Substances Data: 144171-61-9(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 144171-61-9 differently. You can refer to the following data:
1. Indoxacarb is an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.
2. Insecticide.

Hazard

A poison by ingestion. Low toxicity by inhalation and skin contact.

InChI:InChI=1/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3/t21-/m0/s1

Upstream product

• 173903-15-6 chloroformyl(4-trifluoromethoxyphenyl)carbamic acid methyl ester 
• 173903-23-6 C₁₂H₁₁ClN₂O₃ 
• 109-87-5 Dimethoxymethane 
• 79-22-1 methyl chloroformate 
• 461-82-5 4-(trifluoromethoxy)aniline 
• 144171-61-9 methyl 7-chloro-2,3,4a,5-tetrahydro-2-[methoxycarbonyl(4-trifluoromethoxyphenyl)carbamoyl]-indeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate 

Downstream Products

• 144171-61-9 indoxacarb 
• 144171-61-9 (S)-methyl-7-chloro-2,3,4a,5-tetrahydro-2-[methoxycarbonyl(4-trifluoromethoxyphenyl)aminoformyl]indeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate 

Relevant articles and documents

A New Method for the Synthesis of Oxadiazine Insecticide Indoxacarb

9-Fluorenylmethoxycarbonyl was a good protecting group in the field of chemical industry. In the present paper, a new approach for the synthesis of oxadiazine insecticides indoxacarb used 9-fluorenylmethoxycarbonyl as protected group, and triphosgene for chloroformylation. A convenient synthesis of 9-fluorenylmethoxycarbonylhydrazine can be achieved by the nucleophilic substitution reaction of 9-fluorenylmethyl chloroformate and hydrazine hydrate. 4a-Methyl-2-(9-fluorenylmethyl)-7-chloro-indeno [1,2e][1,3,4]oxadia zine-2,4a (3H,5H)-dicarboxylate can be produced via ketone -hydrazine crosslink reaction and cyclization. A preparation of carbamic acid-(chlorocarbonyl)-[(4-trifluoromethoxy) phenyl] me ester can be obtained by the chloroformylation of triphosgene. Finally, the deprotection of 9-fluorenylmethoxy carbonyl and condensation with carbamic acid-(chlorocarbonyl)-[(4-trifluoromethoxy) phenyl] me ester can afford indoxacarb in good yield. A new method for the synthesis of oxadiazine insecticides indoxacarb used 9-fluorenylmethoxycarbonyl-protected group to produce 9-?fluorenylmethoxycarb?onylhydrazine, then through the ketone–hydrazine crosslink reaction, cyclization, deprotection, chloroformylation, and condensation in good yield.

CRYSTALLINE FORM OF INDOXACARB, PROCESS FOR ITS PREPARATION AND USE THEREOF

Provides a crystalline form of indoxacarb, the crystal preparation process, the analyses of the crystal through various analytical methods and using the crystal to prepare stable agrochemical formulation. Also provides the use of various solvents towards