1446141-87-2

Basic information

• Product Name: (1′R,2R,3S,4R)-2-[(1′-phenylsulfonyl)(3′-(4-methoxyphenyl))-propyl]-1-hydroxy-3,4-isopropylidenedioxypyrrolidine
• CAS NO: 1446141-87-2
• Molecular Weight: 447.552
• Mol File: 1446141-87-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1′R,2R,3S,4R)-2-[(1′-phenylsulfonyl)(3′-(4-methoxyphenyl))-propyl]-1-hydroxy-3,4-isopropylidenedioxypyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (1′R,2R,3S,4R)-2-[(1′-phenylsulfonyl)(3′-(4-methoxyphenyl))-propyl]-1-hydroxy-3,4-isopropylidenedioxypyrrolidine(1446141-87-2)
• EPA Substance Registry System: (1′R,2R,3S,4R)-2-[(1′-phenylsulfonyl)(3′-(4-methoxyphenyl))-propyl]-1-hydroxy-3,4-isopropylidenedioxypyrrolidine(1446141-87-2)

Safety Data

• Hazardous Substances Data: 1446141-87-2(Hazardous Substances Data)

Upstream product

• 213598-45-9 3,4-isopropylidenedioxy-Δ¹-pyrroline-1-oxide 
• 1369963-65-4 (3R,3aR,4S,5R)-3-phenylsulfonyl-4,5-isopropylidenedioxy-hexahydropyrrolo[1,2-b]isoxazole 
• 31179-52-9 p-anisylmagnesium bromide 
• 1369963-66-5 (3S,3aR,4S,5R)-3-phenylsulfonyl-4,5-isopropylidenedioxy-hexahydropyrrolo[1,2-b]isoxazole 
• 5535-48-8 PVS 

Relevant articles and documents

Domino elimination/nucleophilic addition in the synthesis of chiral pyrrolidines

Polyhydroxylated pyrrolidines have been synthesized in a one-pot procedure by the addition of an organometallic reagent to isoxazolidines obtained by a 1,3-dipolar cycloaddition between nitrones and vinylsulfones. This method highlights sulfone reactivity and provides an easy approach for the preparation of chiral pyrrolidines using cyclic imines as key intermediates.