144989-61-7Relevant articles and documents
FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF
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Paragraph 0113; 0114, (2019/02/28)
The present invention relates to an FGFR4 inhibitor having a structure represented by formula (I), preparation method therefor, and applications thereof. A series of compounds represented by formula (I) in the present invention have a very-strong inhibiti
A General Route to the Synthesis of N-Protected 1-Substituted and 1,2-Disubstituted Taurines
Xu, Jiaxi,Xu, Shu
, p. 276 - 282 (2007/10/03)
N-Benzyloxycarbonyl protected α-substituted and αβ- disubstituted taurines were synthesized from olefins and epoxides via N-benzyloxycarbonylamino alcohol thioacetates as key intermediates. They are important sulfur analogues of naturally occurring amino acids and building blocks for the synthesis of α-substituted and α,β- disubstituted β-sulfonopeptides.
An Enantiospecific Synthesis of Allosamizoline
Simpkins, Nigel S.,Stokes, Stephen,Whittle, Alan J.
, p. 2471 - 2478 (2007/10/02)
An enantiospecific synthesis of allosamizoline 4, the aglycone of the chitinase inhibitor allosamidin 3, has been achieved, starting from readily available glucosamine.The key step in the synthesis involves the cyclisation of a carbon-centred radical onto