1453-93-6 Usage
General Description
Protopanaxatriol, also known as PPT, is a triterpenoid saponin compound found in the roots of various plants, including ginseng. It has been studied for its potential pharmacological activities, including anti-inflammatory, anti-cancer, and neuroprotective effects. PPT has also been reported to have a positive impact on cardiovascular health and to exhibit anti-diabetic properties. Additionally, research has shown that PPT can enhance the body's immune response and may have potential applications in the treatment of various diseases and conditions. Overall, Protopanaxatriol appears to be a promising compound with diverse potential health benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 1453-93-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,5 and 3 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1453-93:
(6*1)+(5*4)+(4*5)+(3*3)+(2*9)+(1*3)=76
76 % 10 = 6
So 1453-93-6 is a valid CAS Registry Number.
InChI:InChI=1/C30H52O4/c1-18(2)10-9-13-30(8,34)19-11-15-28(6)24(19)20(31)16-22-27(5)14-12-23(33)26(3,4)25(27)21(32)17-29(22,28)7/h10,19-25,31-34H,9,11-17H2,1-8H3/t19-,20+,21-,22+,23-,24-,25-,27+,28+,29+,30-/m0/s1
1453-93-6Relevant articles and documents
Microbial conversion of rare ginsenoside Rf to 20(S)-protopanaxatriol by Aspergillus niger
Liu, Lei,Gu, Li-Juan,Zhang, Dong-Liang,Wang, Zhen,Wang, Chun-Yan,Li, Zheng,Sung, Chang-Keun
, p. 96 - 100 (2010)
In this study, rare ginsenoside Rf was transformed into 20(S)-protopanaxatriol (PPT(S)) by glycosidase from Aspergillus niger. By investing the reaction conditions, the optimal conditions were obtained, as follows: pH 5.0, temperature 55°C, and substrate concentration 1.25 mmol/l. Under optimal conditions, PPT(S) (1.13 μmol) prepared from 1.25 μmol Rf showed a higher yield (90.4%). The enzymatic reaction was analyzed by reversed-phase HPLC, suggesting the transformation pathway: Rf → Rh1(S) → PPT(S).
Three new triterpenoids from Panax ginseng exhibit cytotoxicity against human A549 and Hep-3B cell lines
Ma, Hai-Ying,Gao, Hui-Yuan,Huang, Jian,Sun, Bo-Hang,Yang, Bo
, p. 576 - 582 (2012)
Three new triterpenoid derivatives, 3-O-β-Dglucopyranosyl- 20(S)-protopanaxtriol (1), 3-formyloxy-20-O-b-D-glucopyranosyl-20(S)- protopanaxtriol (2) and 26-hydroxyl-24(E)-20(S)-protopanaxtriol (3), along with six known ginsenosides, were isolated from lea
