1454580-26-7

Basic information

• Product Name: 6-[2-fluoro-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one
• Synonyms: 6-[2-fluoro-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one
• CAS NO: 1454580-26-7
• Molecular Weight: 357.313
• Mol File: 1454580-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-[2-fluoro-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[2-fluoro-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one(1454580-26-7)
• EPA Substance Registry System: 6-[2-fluoro-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one(1454580-26-7)

Safety Data

• Hazardous Substances Data: 1454580-26-7(Hazardous Substances Data)

Upstream product

• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 1454580-25-6 6-[4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one 
• 293741-63-6 6-(2-chloropropanoyl)-2H-1,4-benzoxazin-3(4H)-one 

Relevant articles and documents

Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists

Dihydrofuran-2-one and dihydropyrrol-2-one derivatives were identified as novel, potent and selective mineralocorticoid receptor (MR) antagonists by the structure-based drug design approach utilizing the crystal structure of MR/compound complex. Introduct