145475-99-6Relevant articles and documents
A new synthetic route to 1,5-benzothiazepines. Synthesis of derivatives of diltiazem
Harada,Morimoto,Nagasawa,Takamura,Inoue,Oh-Ihsi,Takeda
, p. 1986 - 1989 (2007/10/02)
Several derivatives of diltiazem (9a-c) have been synthesized from the oxamate (6) through the carbon-carbon ring closure of the sulfur-stabilized benzylic anion and the ester carbonyl group, followed by stereoselective reduction of the C3-carb