146796-02-3

Basic information

• Product Name: HYDROXYMETHYL EDOT
• Synonyms: HYDROXYMETHYL EDOT;(2,3-Dihydrothieno[3,4-b][1,4]dioxin-2-yl)methanol, EDT-methanol, Thieno[3,4-b]-1,4-dioxin-2-methanol;(2,3-Dihydrothieno[3,4-b][1,4]dioxin-2-yl)methanol;EDT-methanol;Thieno[3,4-b]-1,4-dioxin-2-methanol;Thieno[3,4-b]-1,4-dioxin-2-methanol, 2,3-dihydro;HydroxyMethyl EDOT 95%;2,3-dihydro-Thieno[3,4-b]-1,4-dioxin-2-methanol
• CAS NO: 146796-02-3
• Molecular Formula: C₇H₈O₃S
• Molecular Weight: 172.203
• Mol File: 146796-02-3.mol
• Article Data: 16

Chemical Properties

• Melting Point: 42-46 °C
• Boiling Point: 120°C/0.05mmHg(lit.)
• Flash Point: 110 °C
• Appearance: /
• Density: 1.362 g/cm³
• Storage Temp.: 2-8°C
• PKA: 14.10±0.10(Predicted)
• CAS DataBase Reference: HYDROXYMETHYL EDOT(CAS DataBase Reference)
• NIST Chemistry Reference: HYDROXYMETHYL EDOT(146796-02-3)
• EPA Substance Registry System: HYDROXYMETHYL EDOT(146796-02-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 146796-02-3(Hazardous Substances Data)

Usage

Description

Hydroxymethyl EDOT, also known as EDT-methanol, is a conjugated polymer that serves as a precursor to ethylenedioxythiophene (EDOT). It is characterized by the presence of hydroxymethyl groups in the EDOT monomers, which significantly improve the electro-polymerization process in aqueous solutions, leading to the formation of electro-active hydrophilic polymers.

Uses

Used in Polymer Industry:
Hydroxymethyl EDOT is used as a precursor for the synthesis of functional electroactive polymers. The hydroxymethyl groups in the EDOT monomers facilitate the electro-polymerization process, resulting in the formation of hydrophilic polymers with enhanced electrochemical properties.
Used in Electronics Industry:
Hydroxymethyl EDOT is used as a key component in the development of electroactive polymers for various electronic applications, such as sensors, actuators, and energy storage devices. The electrochemical properties of the resulting polymers make them suitable for use in these high-tech applications.
Used in Pharmaceutical Industry:
Hydroxymethyl EDOT can be utilized in the pharmaceutical industry for the development of drug delivery systems. The electro-active hydrophilic polymers formed from Hydroxymethyl EDOT can be used as carriers for drug molecules, improving their solubility, stability, and targeted delivery to specific sites in the body.
Used in Environmental Applications:
Hydroxymethyl EDOT can be employed in environmental applications, such as water treatment and pollution control. The electro-active hydrophilic polymers can be used to adsorb and remove contaminants from water, making them valuable tools in environmental protection and remediation efforts.

Upstream product

• 51792-34-8 2,3-dimethoxythiophene 
• 56-81-5 glycerol 
• 540803-64-3 2-acetoxymethyl-2,3-dihydro-thieno[3,4-b][1,4]dioxine-5,7-dicarboxylic acid dimethyl ester 
• 146796-12-5 2-hydroxymethyl-2,3-dihydrothieno[3,4-b]-[1,4]-dioxin-5,7-dicarboxylic acid dimethyl ester 
• 58416-04-9 3,4-dihydroxythiophene-2,5-dicarboxylic acid dimethyl ester 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 857419-46-6 2-(chloromethyl)-2,3-dihydrothieno[3,4-b][1,4]dioxine 
• 897922-08-6 (2,3-dihydrothieno[3,4-b][1,4]dioxin-3-yl)methyl benzoate 
• 897922-07-5 (2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)methyl acetate 
• 204444-02-0 2-hydroxymethyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5,7-dicarboxylic acid diethyl ester 
• 146796-14-7 2-hydroxymethyl-2,3-dihydrothieno[3,4-b]-[1,4]-dioxin-5,7-dicarboxylic acid 

Downstream Products

• 881759-96-2 (2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)methyl 4-methylbenzenesulfonate 
• 1025483-86-6 11-((2,3-dihydrothieno[3,4-b][1,4]dioxin-3-yl)methyloxy)-3,6,9-trioxaundecyl tosylate 
• 853799-71-0 3-[(2,3-dihydro-thieno[3,4-b][1,4]dioxin-2-yl)methoxy]propionic acid 

Relevant articles and documents

Prussian blue nanoparticles protected by the water-soluble π-conjugated polymer PEDOT-S: Synthesis and multiple-color pH-sensing with a redox reaction

Prussian blue nanoparticles (PB NPs), stabilized for the first time by the π-conjugated polymer poly(4-(2,3-dihydrothieno[3,4-b][1,4]dioxin-2yl-methoxy- 1-butanesulfonic acid, potassium salt) (PEDOT-S), demonstrated a novel multiple-color pH-sensing function with a redox reaction based on the electronic interaction between the PB nano-core and the PEDOT-S shell. The Royal Society of Chemistry 2009.

Electrochemical sensor based on f-SWCNT and carboxylic group functionalized PEDOT for the sensitive determination of bisphenol A

A simple, sensitive, and reliable method for the voltammetric determination of bisphenol A (BPA) by using carboxylic group functionalized single-walled carbon nanotubes (f-SWCNT)/carboxylic-functionalized poly(3,4- ethylenedioxythiophene) (PC4) complex modified glassy carbon electrode (GCE) has been successfully developed. The electrochemical behavior of BPA at the surface of the modified electrode is investigated by electrochemical techniques. The cyclic voltammetry results show that the as-prepared electrode exhibits strong catalytic activity toward the oxidation of BPA with a well-defined anodic peak at 0.623 V in PBS (0.1 mol/L, pH 7.0). The surface morphology of the 3D network of composite film is beneficial for the adsorption of analytes. Under the optimized conditions, the oxidation peak current is proportional to BPA concentration in the range between 0.099 and 5.794 μmol/L (R2 = 0.9989), with a limit of detection of 0.032 μmol/L (S/N = 3). The enhanced performance of the sensor can be attributed to the excellent electrocatalytic property of f-SWCNT and the extraordinary conductivity of PC4. Furthermore, the proposed modified electrode displays high stability and good reproducibility. The good result on the voltammetric determination of BPA also indicates that the as-fabricated modified electrode will be a good candidate for the electrochemical determination and analysis of BPA.

Method for preparing thieno[3,4-B]-1,4-dioxin-2-methanol

The invention relates to a method for preparing thieno[3,4-B]-1,4-dioxin-2-methanol. The method comprises the following steps: adding dimethyl 3,4-dihydroxythiophene-2,5-dicarboxylate, 2,3-dibromo-1-propanol and an organic amine catalyst into an organic solvent for heating reaction, and carrying out post treatment to obtain dimethyl 2-hydroxymethyl-2,3-dihydrothieno[3,4-b]-[1,4]-dioxin-5,7-dicarboxylate; adding the dimethyl 2-hydroxymethyl-2,3-dihydrothieno[3,4-b]-[1,4]-dioxin-5,7-dicarboxylate into an organic solvent for dispersion, then adding Lewis acid, water and vanadium oxide or a supported catalyst thereof, carrying heating and stirring for reaction, and carrying out post treatment to obtain thieno[3,4-B]-1,4-dioxin-2-methanol. The method for preparing thieno[3,4-B]-1,4-dioxin-2-methanol, provided by the invention, has the advantages of short reaction route, high product yield and low cost.

Method for synthesizing hydroxymethyl EDOT (Ethylenedioxythiophene)

The invention relates to a method for synthesizing hydroxymethyl EDOT (Ethylenedioxythiophene). The method comprises the following steps: 3,4-dihydroxythiophene-2,5-dimethyl isophthalate, glycerol andcatalyst are heated to react in organic solvent to obtain 2-hydroxymethyl-2,3-dihydrothiophene[3,4-b]-[1,4]-dioxin-5,7-methyl diformate; the 2-hydroxymethyl-2,3-dihydrothiophene[3,4-b]-[1,4]-dioxin-5,7-2-methyl diformate is added into strong base aqueous solution to be subjected to heating reaction; then, strong acid aqueous solution is used for acidification to obtain 2-hydroxymethyl-2,3-dihydrothiophene[3,4-b]-[1,4]-dioxin-5,7-dicarboxylic acid; the 2-hydroxymethyl-2,3-dihydrothiophene[3,4-b]-[1,4]-dioxin-5,7-methyl diformate and catalyst are heated to react in organic solvent to obtain thehydroxymethyl EDOT. The method disclosed by the invention has the advantages of short reaction line, high product yield and low cost.