1482494-92-7Relevant articles and documents
Cephalosporolide B serving as a versatile synthetic precursor: Asymmetric biomimetic total syntheses of cephalosporolides C, E, F, G, and (4-OMe-)G
Song, Liyan,Liu, Yuan,Tong, Rongbiao
, p. 5850 - 5853 (2013)
Cephalosporolide B (Ces-B) was efficiently synthesized and exploited for the first time as a versatile biomimetic synthetic precursor for the chemical syntheses of not only cephalosporolides C, G, and (4-OMe-) G via a challenging diastereoselective oxa-Michael addition but also the structurally unprecedented cephalosporolides E and F via a novel biomimetic ring-contraction rearrangement. These findings provide the first direct chemical evidence that Ces-B may be the true biosynthetic precursor of cephalosporolides.