149554-03-0

Basic information

• Product Name: 1-(TERT-BUTOXYCARBONYLMETHYL)-4-PIPERIDINONE
• Synonyms: 1-(TERT-BUTOXYCARBONYLMETHYL)-4-PIPERIDINONE;tert-Butyl (4-oxopiperidin-1-yl)acetate;tert-Butyl 2-(4-oxopiperidin-1-yl)acetate
• CAS NO: 149554-03-0
• Molecular Formula: C₁₁H₁₉NO₃
• Molecular Weight: 213.27
• Mol File: 149554-03-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 308.1±27.0 °C(Predicted)
• Appearance: /
• Density: 1.060±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 5.48±0.20(Predicted)
• CAS DataBase Reference: 1-(TERT-BUTOXYCARBONYLMETHYL)-4-PIPERIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(TERT-BUTOXYCARBONYLMETHYL)-4-PIPERIDINONE(149554-03-0)
• EPA Substance Registry System: 1-(TERT-BUTOXYCARBONYLMETHYL)-4-PIPERIDINONE(149554-03-0)

Safety Data

• Hazardous Substances Data: 149554-03-0(Hazardous Substances Data)

Usage

General Description

1-(tert-butoxycarbonylmethyl)-4-piperidinone, also known as Boc-Pip-One, is a chemical compound used in the synthesis of pharmaceuticals and agrochemicals. It is a versatile building block with numerous applications in organic chemistry. The compound has a Boc (tert-butoxycarbonyl) protecting group attached to the nitrogen atom of a piperidinone ring, making it an important intermediate in the production of various pharmaceuticals and fine chemicals. Boc-Pip-One is commonly utilized in the construction of biologically active molecules and has demonstrated potential for use in the development of new medications and agrochemical products.

Upstream product

• 107-59-5 tert-Butyl chloroacetate 
• 40064-34-4 piperidine-4,4-diol hydrochloride 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 41979-39-9 4-piperidone hydrochloride 
• 41661-47-6 piperidin-4-one 

Downstream Products

• 149554-31-4 (4-{4-[4-(N-Hydroxycarbamimidoyl)-phenyl]-piperazin-1-yl}-piperidin-1-yl)-acetic acid tert-butyl ester 
• 149554-04-1 {4-[4-(4-Cyano-phenyl)-piperazin-1-yl]-piperidin-1-yl}-acetic acid tert-butyl ester 

Relevant articles and documents

Ring derivative of inhibitor for bromodomains in bromodomain and extra-teminal domain (BET) family, and preparation method and pharmaceutical application of ring derivative

The invention relates to a compound as shown in a general formula (I) or a stereoisomer, a deuterated compound, a solvate, a prodrug, a metabolite, a pharmaceutically acceptable salt or an eutectic crystal thereof, an intermediate and a preparation method of the compound or the stereoisomer, the deuterated compound, the solvate, the prodrug, the metabolite, the pharmaceutically acceptable salt orthe eutectic crystal thereof, and application of the compound or the stereoisomer, the deuterated compound, the solvate, the prodrug, the metabolite, the pharmaceutically acceptable salt or the eutectic crystal thereof in inhibiting or degrading diseases related to the bromodomains in the BET family. The formula (I) is B-L-K.

FREE-STANDING NON-FOULING POLYMERS, THEIR COMPOSITIONS, AND RELATED MONOMERS

Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions.