151449-78-4

Basic information

• Product Name: 4-HYDROXY-1-METHYL-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID (2-AMINO-PHENYL)-AMIDE
• Synonyms: 4-HYDROXY-1-METHYL-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID (2-AMINO-PHENYL)-AMIDE;4-Hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid (2-aminopheyl)ami;N-(2-aminophenyl)-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamide
• CAS NO: 151449-78-4
• Molecular Formula: C₁₇H₁₅N₃O₃
• Molecular Weight: 309.32
• Mol File: 151449-78-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 524.6°C at 760 mmHg
• Flash Point: 271°C
• Appearance: /
• Density: 1.466g/cm³
• Vapor Pressure: 7.85E-12mmHg at 25°C
• Refractive Index: 1.75
• CAS DataBase Reference: 4-HYDROXY-1-METHYL-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID (2-AMINO-PHENYL)-AMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-1-METHYL-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID (2-AMINO-PHENYL)-AMIDE(151449-78-4)
• EPA Substance Registry System: 4-HYDROXY-1-METHYL-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID (2-AMINO-PHENYL)-AMIDE(151449-78-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 151449-78-4(Hazardous Substances Data)

Usage

Description

4-Hydroxy-1-methyl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid (2-amino-phenyl)-amide is a synthetic derivative of quinoline, a heterocyclic compound with potential pharmaceutical applications. 4-HYDROXY-1-METHYL-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID (2-AMINO-PHENYL)-AMIDE features a hydroxy group, a methyl group, and an oxo group in its structure, along with an amino-phenyl amide side chain. Its unique molecular composition makes it an interesting candidate for further research and development as a potential drug for treating various conditions.

Uses

Used in Pharmaceutical Industry:
4-Hydroxy-1-methyl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid (2-amino-phenyl)-amide is used as a potential drug candidate for the treatment of various conditions due to its unique molecular structure and synthetic origin from quinoline, a compound known for its pharmacological activity.
Further research and testing would be required to determine the precise pharmacological properties and potential therapeutic applications of this compound, as it has not yet been established for specific uses. Its development could lead to new treatments and therapies in the pharmaceutical industry, depending on the outcomes of such studies.

InChI:InChI=1/C17H15N3O3/c1-20-13-9-5-2-6-10(13)15(21)14(17(20)23)16(22)19-12-8-4-3-7-11(12)18/h2-9,23H,18H2,1H3,(H,19,22)

Upstream product

• 119-68-6 N-Methylanthranilic acid 
• 95-54-5 1,2-diamino-benzene 
• 84088-50-6 4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid methyl ester 
• 57513-54-9 ethyl 4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 

Relevant articles and documents

Synthesis, X-ray crystallographic study, and biological evaluation of coumarin and quinolinone carboxamides as anticancer agents

A series of coumarin and quinolinone-3-aminoamide derivatives was synthesized and evaluated for its potency in inhibition of cancer cell growth. The structure of N-[2-(dimethylamino) ethyl]-4-hydroxy-2-oxo-1-phenyl-1,2- dihydroquinoline-3-carboxamide was

4-HYDROXY-2-QUINOLONES 7. SYNTHESIS AND BIOLOGICAL PROPERTIES OF 1-R-3-(2-BENZIMIDAZOLYL)-4-HYDROXY-2-QUINOLONES

Condensation of 1-R-3-carbethoxy-4-hydroxy-2-quinolones with o-phenylene diamine gives the corresponding 1-R-3-(2-benzimidazolyl)-4-hydroxy-2-quinolones.Data on a study of the antihyroid activity of the synthesized compounds is presented.