152299-00-8

Basic information

• Product Name: (S)-N,N-dibenzyl-2-<1-tert-butyldimethylsilyloxy-4-(1-pyrazolyl)>butylamine
• Synonyms: (S)-N,N-dibenzyl-2-<1-tert-butyldimethylsilyloxy-4-(1-pyrazolyl)>butylamine
• CAS NO: 152299-00-8
• Molecular Weight: 449.712
• Mol File: 152299-00-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-N,N-dibenzyl-2-<1-tert-butyldimethylsilyloxy-4-(1-pyrazolyl)>butylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N,N-dibenzyl-2-<1-tert-butyldimethylsilyloxy-4-(1-pyrazolyl)>butylamine(152299-00-8)
• EPA Substance Registry System: (S)-N,N-dibenzyl-2-<1-tert-butyldimethylsilyloxy-4-(1-pyrazolyl)>butylamine(152299-00-8)

Safety Data

• Hazardous Substances Data: 152299-00-8(Hazardous Substances Data)

Upstream product

• 159497-65-1 N,N-dibenzylasparaginic acid dibenzyl ester 
• 137428-32-1 (2S)-2-[bis(phenylmethyl)amino]-1,4-butanediol 
• 161531-12-0 (S)-1-(3-N,N-dibenzylamino-4-hydroxy)butylmethanesulfonate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 288-13-1 NH-pyrazole 
• 152298-86-7 (S)-1-(3-N,N-dibenzylamino-4-tert-butyldimethylsilyloxy)butylmethanesulfonate 
• 40802-36-6 potassium pyrazolide 

Downstream Products

• 152298-89-0 (S)-2-N,N-dibenzylamino-4-(1-pyrazolyl)butanal 
• 152299-08-6 (S)-2-N,N-dibenzylamino-4-(1-pyrazolyl)-1-butanol 

Relevant articles and documents

2-Dibenzylaminobutane-1,4-diol: An Effective Chiral Building Block for the Synthesis of 1,2-Amino Alcohols

Regioselective activation and protection of the chiral building block 1, readly available from L-aspartic acid, leads to the key intermediate 8.Employing classical nucleophiles, heterocyclic anions or organocuprates, 8 could be transformed into the displa