152302-94-8

Basic information

• Product Name: N-(2-Iodophenyl)-α-(diethoxyphosphinyl)acetamide
• Synonyms: N-(2-Iodophenyl)-α-(diethoxyphosphinyl)acetamide
• CAS NO: 152302-94-8
• Molecular Weight: 397.15
• Mol File: 152302-94-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(2-Iodophenyl)-α-(diethoxyphosphinyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Iodophenyl)-α-(diethoxyphosphinyl)acetamide(152302-94-8)
• EPA Substance Registry System: N-(2-Iodophenyl)-α-(diethoxyphosphinyl)acetamide(152302-94-8)

Safety Data

• Hazardous Substances Data: 152302-94-8(Hazardous Substances Data)

Upstream product

• 615-43-0 2-iodophenylamine 
• 1026051-79-5 triethyl phosphite 
• 1339628-12-4 N-(2-iodophenyl)-2-bromoacetamide 
• 3095-95-2 diethylphosphonoacetic acid 

Downstream Products

• 59066-62-5 (E)-2-styrylbenzoxazole 
• 1122478-35-6 rac-3-(8-ethyl-3-formyl-5,6,7,8-tetrahydroindolizin-8-yl)-N-(2-iodophenyl)propanamide 
• 1243657-73-9 (E)-3-(cyclohexylmethylene)indolin-2-one 
• 1243657-82-0 (Z)-3-(cyclohexylmethylene)indolin-2-one 
• 29551-52-8 3-[(E)-(4-chlorophenyl)methylidene]-1,3-dihydro-2H-indol-2-one 
• 194413-58-6 semaxanib 
• 64264-46-6 3-[(furan-2-yl)methylene]-2-indolinone 
• 64264-45-5 (3E)-3-(2-furylmethylidene)-1H-indol-2(3H)-one 

Relevant articles and documents

Formal Total Synthesis of (±)-Rhazinal: Evaluating the Radical Approach

We describe a formal total synthesis of the racemic natural product rhazinal by a rapid elaboration of a recently reported tetrahydroindolizine intermediate into the cyclization precursor reported by Trauner. The synthesis focuses on the early and convergent introduction of functional groups while the synthetic challenges encountered by this approach are described.

Copper(I) Salt-Mediated Arylation of Phosphinyl-Stabilized Carbanions and Synthetic Application to Heterocyclic Compounds

The copper-mediated reaction of phosphinyl-stabilized carbanions 2a-c with aryl halides 1a-i in DMF or HMPA produced (arylmethyl)phosphonates 3-11 in good yields.Similar treatment of N-(2-iodophenyl)- and N-(2-iodophenyl)-N-methyl-α-(diethoxyphosphinyl)ac