153004-31-0 Usage
General Description
The chemical compound "(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol" is a synthetic estrogen derivative that belongs to the family of nonsteroidal selective estrogen receptor modulators (SERMs). It is a potent and selective agonist for the estrogen receptor alpha, with potential applications in the treatment of hormone-sensitive cancers such as breast cancer. (7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol has been studied for its ability to induce apoptosis in estrogen receptor-positive breast cancer cells and inhibit the proliferation of cancer cells. It also has potential as a therapy for osteoporosis and postmenopausal symptoms. The chemical structure of this compound includes a nonyl-thio chain and a pentafluoropentyl substituent, contributing to its specific binding and activity at the estrogen receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 153004-31-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,0,0 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 153004-31:
(8*1)+(7*5)+(6*3)+(5*0)+(4*0)+(3*4)+(2*3)+(1*1)=80
80 % 10 = 0
So 153004-31-0 is a valid CAS Registry Number.
153004-31-0Relevant articles and documents
An Efficient Regioselective Preparation of Fulvestrant
Pichandi Mohanraj, Senthil Kumar,Tulasi, Ramachar,Chidambaram Subramanian, Venkatesan
, p. 362 - 368 (2021/07/26)
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Processes and intermediates for preparing fulvestrant
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, (2020/05/30)
The present invention provides a method and an intermediate for preparing fulvestrant, and relates to a method for preparing fulvestrant, and an intermediate (5) of fulvestrant, and a synthetic methodthereof. The method provided by the invention can be used for obtaining high-purity fulvestrant, and is suitable for industrial mass production.
Fulvestrant intermediate
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, (2019/10/01)
The present invention provides a new fulvestrant intermediate compound represented by a formula III, wherein the mass spectrum of the intermediate III is [M+H]237.2082. According to the present invention, with the application of the intermediate to prepare fulvestrant, the route is simple, the yield and the purity of each reaction intermediate are high, the high-purity fulvestrant can be obtained through re-crystallization without column chromatography, and the method is suitable for industrial production.