153235-85-9

Basic information

• Product Name: N⁶-4-monomethoxytrityl-9-[2-(diethylphosphonylmethoxy)ethyl]adenine
• Synonyms: N⁶-4-monomethoxytrityl-9-[2-(diethylphosphonylmethoxy)ethyl]adenine
• CAS NO: 153235-85-9
• Molecular Weight: 601.642
• Mol File: 153235-85-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N⁶-4-monomethoxytrityl-9-[2-(diethylphosphonylmethoxy)ethyl]adenine(CAS DataBase Reference)
• NIST Chemistry Reference: N⁶-4-monomethoxytrityl-9-[2-(diethylphosphonylmethoxy)ethyl]adenine(153235-85-9)
• EPA Substance Registry System: N⁶-4-monomethoxytrityl-9-[2-(diethylphosphonylmethoxy)ethyl]adenine(153235-85-9)

Safety Data

• Hazardous Substances Data: 153235-85-9(Hazardous Substances Data)

Upstream product

• 116384-53-3 [[2-(6-amino-9H-purine-9-yl)ethoxy]methyl]phosphonic acid diethyl ester 
• 14470-28-1 mono-4-methoxytrityl chloride 

Downstream Products

• 872191-12-3 N⁶-4-monomethoxytrityl-9-{2-[(3,5-di-tert-butyl-cycloSal)phosphonylmethoxy]ethyl}adenine 
• 872191-10-1 N⁶-4-monomethoxytrityl-9-{2-[(3-tert-butyl-cycloSal)phosphonylmethoxy]ethyl}adenine 
• 872191-08-7 N⁶-4-monomethoxytrityl-9-{2-[(3-methyl-cycloSal)phosphonylmethoxy]ethyl}adenine 
• 872191-06-5 N⁶-4-monomethoxytrityl-9-[2-(cycloSal-phosphonylmethoxy)ethyl]adenine 

Relevant articles and documents

CycloSal-PMEA and cycloAmb-PMEA: Potentially new phosphonate prodrugs based on the cyclosal-pronucleotide approach

Two new classes of lipophilic prodrugs of the antiviral active phosphonate 9-[2-phosphonomethoxyethyl]adenine (PMEA 1) have been prepared and were studied with regard to their hydrolysis properties and biological activity. A first series of compounds was