872191-12-3

Basic information

• Product Name: N⁶-4-monomethoxytrityl-9-{2-[(3,5-di-tert-butyl-cycloSal)phosphonylmethoxy]ethyl}adenine
• Synonyms: N⁶-4-monomethoxytrityl-9-{2-[(3,5-di-tert-butyl-cycloSal)phosphonylmethoxy]ethyl}adenine
• CAS NO: 872191-12-3
• Molecular Weight: 745.858
• Mol File: 872191-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N⁶-4-monomethoxytrityl-9-{2-[(3,5-di-tert-butyl-cycloSal)phosphonylmethoxy]ethyl}adenine(CAS DataBase Reference)
• NIST Chemistry Reference: N⁶-4-monomethoxytrityl-9-{2-[(3,5-di-tert-butyl-cycloSal)phosphonylmethoxy]ethyl}adenine(872191-12-3)
• EPA Substance Registry System: N⁶-4-monomethoxytrityl-9-{2-[(3,5-di-tert-butyl-cycloSal)phosphonylmethoxy]ethyl}adenine(872191-12-3)

Safety Data

• Hazardous Substances Data: 872191-12-3(Hazardous Substances Data)

Upstream product

• 14470-28-1 mono-4-methoxytrityl chloride 
• 116384-53-3 [[2-(6-amino-9H-purine-9-yl)ethoxy]methyl]phosphonic acid diethyl ester 
• 153235-85-9 N⁶-4-monomethoxytrityl-9-[2-(diethylphosphonylmethoxy)ethyl]adenine 
• 16373-02-7 2,4-di-tert-butyl-6-hydroxymethylphenol 

Relevant articles and documents

CycloSal-PMEA and cycloAmb-PMEA: Potentially new phosphonate prodrugs based on the cyclosal-pronucleotide approach

Two new classes of lipophilic prodrugs of the antiviral active phosphonate 9-[2-phosphonomethoxyethyl]adenine (PMEA 1) have been prepared and were studied with regard to their hydrolysis properties and biological activity. A first series of compounds was