153381-68-1

Basic information

• Product Name: 7-Epi-docetaxel (Docetaxel Impurity C)
• Synonyms: (2b,5b,7a,10b,13a)-4-Acetoxy-13-(((2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl)oxy)-1,7,10-trihydroxy- 9-oxo-5,20-epoxytax-11-en-2-yl Benzoate;7-Epidocetaxel;7-Epi-docetaxel (Docetaxel Impurity C);7-Epitaxotere;Docetaxel Impurity C;Docetaxel EP Impurity C
• CAS NO: 153381-68-1
• Molecular Formula: C₄₃H₅₃NO₁₄
• Molecular Weight: 807.87922
• Product Categories: Chemical Impurities;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;Inhibitors
• Mol File: 153381-68-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 138-140°C
• Boiling Point: 900.5±65.0 °C(Predicted)
• Appearance: /
• Density: 1.37±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Amber Vial, -20?C Freezer, Under Inert Atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 11.20±0.46(Predicted)
• CAS DataBase Reference: 7-Epi-docetaxel (Docetaxel Impurity C)(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Epi-docetaxel (Docetaxel Impurity C)(153381-68-1)
• EPA Substance Registry System: 7-Epi-docetaxel (Docetaxel Impurity C)(153381-68-1)

Safety Data

• Hazardous Substances Data: 153381-68-1(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 153381-68-1 differently. You can refer to the following data:
1. 7-Epi Docetaxel (Docetaxel EP Impurity C) is an isomer of Docetaxel (D494420). Docetaxel injection impurity C.
2. An isomer of Docetaxel. Docetaxel injection impurity C
3. An isomer of Docetaxel (D494420). Docetaxel injection

Upstream product

• 114915-20-7 Docetaxel 

Relevant articles and documents

Preparation method 10 - carbonyl docetaxel

The invention discloses a preparation method of 10 - carbonyl docetaxel, and the technical scheme of the invention comprises the following steps: S1: dissolving docetaxel solvent, adding heavy metal salt, stirring and reacting, carrying out suction filtra

Method for preparing 7-epi-taxane compounds

The invention relates to a method for preparing 7-epi-taxane compounds from 7-beta-hydroxy taxane compounds. The method comprises the step of converting 7-beta-hydroxy taxane compounds into 7-epi-taxane compounds in the solvent S under the existence of a

PHARMACEUTICAL COMPOSITION CONTAINING A TAXANE DERIVATIVE, DESTINED FOR THE PREPARATION OF AN INFUSION SOLUTION, METHOD OF PREPARATION THEREOF AND USE THEREOF

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