15366-27-5

Basic information

• Product Name: Benzoyl-L-alanin-hydrazid
• Synonyms: Benzoyl-L-alanin-hydrazid
• CAS NO: 15366-27-5
• Molecular Weight: 207.232
• Mol File: 15366-27-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoyl-L-alanin-hydrazid(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl-L-alanin-hydrazid(15366-27-5)
• EPA Substance Registry System: Benzoyl-L-alanin-hydrazid(15366-27-5)

Safety Data

• Hazardous Substances Data: 15366-27-5(Hazardous Substances Data)

Upstream product

• 5446-46-8 ethyl 2-(benzoylamino)propanoate 
• 65-85-0 benzoic acid 
• 51127-13-0 2-phenyl-4-methyl-4H-oxazolin-5-one 
• 32619-69-5 L-Alanine, N-benzoyl-, ethyl ester 
• 98-88-4 benzoyl chloride 
• 7244-67-9 N-benzoyl-L-alanine methyl ester 
• 2198-64-3 N-benzoyl-L-alanine 

Downstream Products

• 93874-59-0 2-benzoylamino-5-(1-benzoylamino-ethyl)-[1,3,4]oxadiazole 
• 92136-47-5 2-benzoylaminopropionic acid prop-2-ynyl ester 
• 91089-20-2 N-[1-(5-amino-[1,3,4]oxadiazol-2-yl)-ethyl]-benzamide 
• 15366-23-1 N,N'-bis-(N-benzoyl-alanyl)-hydrazine 

Relevant articles and documents

Synthesis of Hydrazones from Amino Acids and their Antimicrobial and Cytotoxic Activities

Hydrazones 6a–6n were synthesized from different amino acids with various aldehydes under reflux in methanol/ethanol. The structures of synthesized compounds were ascertained by elemental analysis and spectroscopic techniques. A comparative study of the antimicrobial activity and cytotoxicity was carried out of the N-protected amino acids, their esters, hydrazides, and the respective hydrazones, providing good results in cytotoxicity studies.

Synthesis and antitumor evaluation of some 1,3,4-oxadiazole-2(3H)-thione and 1,2,4-triazole-5(1H)-thione derivatives

A series of 1,3,4-oxadiazole-2-thione and 1,2,4-triazole-5-thione derivatives have been successfully synthesized and studied for their antitumor activity. These compounds were prepared from carboxylic acids and chiral aminoacid esters. The prepared compounds were evaluated for their cytotoxicity against cancer in vitro using hydroxyurea (HU) as positive control. A fair number of compounds were found to have significant antitumor activity. To study the molecular basis of interaction and affinity of binding of the target molecules, all the compounds were docked into the ATPase domain of TP-II and tubulin using Schroedinger. Springer Science+Business Media, LLC 2010.