1537171-26-8

Basic information

• Product Name: 4-(4-chlorophenyl)-4H-spiro[benzo[d][1,2]dioxine-1,1'-cyclohexan]-4-amine
• Synonyms: 4-(4-chlorophenyl)-4H-spiro[benzo[d][1,2]dioxine-1,1'-cyclohexan]-4-amine
• CAS NO: 1537171-26-8
• Molecular Weight: 329.826
• Mol File: 1537171-26-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-chlorophenyl)-4H-spiro[benzo[d][1,2]dioxine-1,1'-cyclohexan]-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenyl)-4H-spiro[benzo[d][1,2]dioxine-1,1'-cyclohexan]-4-amine(1537171-26-8)
• EPA Substance Registry System: 4-(4-chlorophenyl)-4H-spiro[benzo[d][1,2]dioxine-1,1'-cyclohexan]-4-amine(1537171-26-8)

Safety Data

• Hazardous Substances Data: 1537171-26-8(Hazardous Substances Data)

Upstream product

• 221626-01-3 2-cyclohexyl-1-cyanobenzene 
• 873-77-8 (4-chlorphenyl)magnesium bromide 

Relevant articles and documents

ENDOPEROXIDES, SYNTHESIS AND USES THEREOF FOR THE TREATMENT OF NEOPLASTIC DISEASES SUCH AS CANCER

The present invention generally relates to processes and methods for the synthesis of endoperoxide compounds. More specifically, the invention relates to a method for preparing endoperoxide compounds starting from an aryl imine of formula (I) in the presence of a metallic catalyst and oxygen. The present invention also relates to endoperoxide compounds of formula (III) and their pharmaceutically acceptable salts thereof, useful for therapy. All substituents are defined herein. Also disclosed are methods of treating cancer using the compounds of formula (III).