153749-83-8Relevant articles and documents
Acyl/aroyl Meldrum's acid as an enol surrogate for the direct organocatalytic synthesis of α,β-unsaturated ketones
Khopade, Tushar M.,Warghude, Prakash K.,Mete, Trimbak B.,Bhat, Ramakrishna G.
, p. 197 - 200 (2018/12/13)
The operationally simple, robust and straightforward organocatalytic protocol is developed for the synthesis of E-selective α,β-unsaturated ketones. The method utilizes simple and easily accessible starting materials such as Meldrum's acid, carboxylic acid, aldehyde and simple bifunctional amine catalyst. The tandem organocatalytic process utilizes acyl/aroyl Meldrum's acid as an enol surrogate for the effective Doebner-Knoevenagel type condensation reactions. A wide variety of aldehydes, carboxylic acids and base sensitive functional groups are well tolerated under the mild reaction conditions.
Method for preparing beta-aminoketone by photoinduced nonmetallic catalysis
-
Paragraph 0069-0072, (2019/01/14)
The invention discloses a method for preparing beta-aminoketone by photoinduced nonmetallic catalysis. The method comprises steps as follows: in the presence of simple iodine salt, phosphine ligands and an organic solvent, decarboxylation of active carbox
Nickel-catalyzed sp3 C-H bond activation from decarboxylative cross-coupling of α,β-unsaturated carboxylic acids with amides
Zhang, Jia-Xiang,Wang, Yan-Jing,Wang, Nai-Xing,Zhang, Wei,Bai, Cui-Bing,Li, Yi-He,Wen, Jia-Long
, p. 1621 - 1625 (2014/07/08)
Nickel-catalyzed functionalization of C(sp3)-H bonds adjacent to a nitrogen atom in amides through decarboxylative cross-coupling of α,β-unsaturated carboxylic acids is reported. A possible reaction mechanism is proposed that involves radical intermediate species. Georg Thieme Verlag Stuttgart, New York.
