82961-73-7

Basic information

• Product Name: 1,3-Dioxane-4,6-dione, 5-(hydroxyphenylmethylene)-2,2-dimethyl-
• CAS NO: 82961-73-7
• Molecular Formula: C13H12O5
• Molecular Weight: 248.235
• Mol File: 82961-73-7.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxane-4,6-dione, 5-(hydroxyphenylmethylene)-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-4,6-dione, 5-(hydroxyphenylmethylene)-2,2-dimethyl-(82961-73-7)
• EPA Substance Registry System: 1,3-Dioxane-4,6-dione, 5-(hydroxyphenylmethylene)-2,2-dimethyl-(82961-73-7)

Safety Data

• Hazardous Substances Data: 82961-73-7(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 707-07-3 orthobenzoic acid trimethyl ester 
• 112182-61-3 5-(1-methylsulfanyl-1-phenylmethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 93-97-0 benzoic acid anhydride 
• 212068-02-5 methoxybenzylidene Meldrum's acid 

Downstream Products

• 84794-37-6 N-(3-Oxo-3-phenyl-propionyl)-isonicotinamide 
• 15231-17-1 N-benzoylbenzoylacetamide 
• 148433-19-6 N-(3-oxo-3-phenylpropanoyl)-L-homoserine lactone 
• 7733-48-4 N-acetylbenzoylacetamide 
• 10300-07-9 N-Propionyl-α-benzoylacetamid 
• 614-27-7 methyl 3-oxo-3-phenylpropionate 
• 4845-49-2 1,3-diphenyl-5-oxo-4,5-dihydro-1H-pyrazole 
• 1479-22-7 ethyl 2-fluoro-3-oxo-3-phenylpropionate 
• 450-95-3 2-fluoroacetophenone 
• 153749-83-8 2-(2-oxo-2-phenyl-ethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 39511-11-0 (E)-1-phenyl-3-(thiophen-2-yl)-2-propen-1-one 
• 2960-55-6 (E)-3-(4-nitrophenyl)-1-phenylprop-2-en-1-one 
• 22252-15-9 trans-4-methoxychalcone 
• 614-47-1 1,3-diphenyl-propen-3-one 

Relevant articles and documents

Electrochemical synthesis of versatile ammonium oxides under metal catalyst-, exogenous-oxidant-, and exogenous-electrolyte-free conditions

An electrochemical oxidative cross-coupling reaction between 2.5-substituted-pyrazolin-5-ones and ammonium thiocyanate has been developed, which resulted in a series of unprecedented cross-coupling products under metal catalyst-, exogenous-oxidant-, and exogenous-electrolyte-free conditions. It is worth noting that since the resulting cross-coupling products are nearly insoluble in MeCN, the pure product could be afforded without silica gel column purification. In addition, the prepared ammonium oxides are versatile building blocks for synthesizing functionalized pyrazole derivatives.

5-Carbonyl-1,3-oxazine-2,4-diones from N-Cyanosulfoximines and Meldrum's Acid Derivatives

At elevated temperatures, N-cyanosulfoximines react with Meldrum's acid derivatives to give sulfoximines with N-bound 5-carbonyl-1,3-oxazine-2,4-dione groups. A representative product was characterized by single-crystal X-ray structure analysis. The product formation involves an unexpected molecular reorientation requiring several sequential bond-forming and-cleaving processes.

Chiral synthesis method for chiral beta-amino acid and synthesis method for medicinal intermediate

The invention relates to a chiral synthesis method for chiral beta-amino acid. The chiral synthesis method comprises the following steps: reacting a compound shown in formula (II) with an acylation reagent to prepare anhydride intermediate reaction liquid under the action of alkali; adding Meldrum's acid into the anhydride intermediate reaction liquid, and performing reaction to generate a compound shown in formula (III); reacting the compound shown in formula (III) with a compound shown in formula (IV) to generate a compound shown in formula (V); reducing the compound shown in formula (V) to generate a compound shown in formula (VI); performing acidic hydrolysis on the compound shown in formula (VI) to generate a compound shown in formula (I), i.e., the chiral beta-amino acid. The chiral synthesis method has the advantages of convenience for synthesis, low cost and simple process, and compared with a disclosed preparation method, is more suitable for industrial production.