1542256-76-7Relevant articles and documents
Synthesis, docking simulation, biological evaluations and 3D-QSAR study of 5-Aryl-6-(4-methylsulfonyl)-3-(metylthio)-1,2,4-triazine as selective cyclooxygenase-2 inhibitors
Irannejad, Hamid,Kebriaieezadeh, Abbas,Zarghi, Afshin,Montazer-Sadegh, Farhad,Shafiee, Abbas,Assadieskandar, Amir,Amini, Mohsen
, p. 865 - 873 (2014)
A series of 5-Aryl-6-(4-methylsulfonyl)-3-(metylthio)-1,2,4-triazine derivatives were synthesized and their COX-1/COX-2 inhibitory activity as well as in vivo anti-inflammatory and analgesic effects were evaluated. All of compounds showed strong inhibitio