15485-65-1Relevant articles and documents
Microwave-promoted synthesis of polyhydroxydeoxybenzoins in ionic liquids
Hakala, Ullastiina,W?h?l?, Kristiina
, p. 8375 - 8378 (2006)
A microwave-promoted synthesis of polyhydroxydeoxybenzoins and -phenylpropanones has been developed, using bis{(trifluoromethyl)sulfonyl}amine (HNTf2) or BF3·OEt2 in an ionic liquid solvent.
Identification of enterodiol as a masker for caffeine bitterness by using a pharmacophore model based on structural analogues of homoeriodictyol
Ley, Jakob P.,Dessoy, Marco,Paetz, Susanne,Blings, Maria,Hoffmann-Lücke, Petra,Reichelt, Katharina V.,Krammer, Gerhard E.,Pienkny, Silke,Brandt, Wolfgang,Wessjohann, Ludger
, p. 6303 - 6311 (2012)
Starting from previous structure-activity relationship studies of taste modifiers based on homoeriodictyol, dihydrochalcones, deoxybenzoins, and trans-3-hydroxyflavones as obvious analogues were investigated for their masking effect against caffeine. The most active compounds of the newly investigated taste modifiers were phloretin, the related dihydrochalcones 3-methoxy-2′,4,4′-trihydroxydihydrochalcone and 2′,4- dihydroxy-3-methoxydihydrochalcone, and the deoxybenzoin 2-(4-hydroxy-3- methoxyphenyl)-1-(4-hydroxyphenyl)ethanone. Starting with the whole set of compounds showing activity >22%, a (Q)SAR pharmacophore model for maskers of caffeine bitterness was calculated to explain the structural requirements. After docking of the pharmacophore into a structural model of the broadly tuned bitter receptor hTAS2R10 and docking of enterolactone and enterodiol as only very weakly related structures, it was possible to predict qualitatively their modulating activity. Enterodiol (25 mg L-1) reduced the bitterness of the 500 mg L-1 caffeine solution by about 30%, whereas enterolactone showed no masking but a slight bitter-enhancing effect.
Multifunctional deoxybenzoin-based monomers and resins having reduced flammability
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Page/Page column 10, (2016/08/10)
The invention provides a novel platform for minimal- or non-flammable polymers, which is based purely on hydrocarbon systems and does not need additives of any kind A key feature is that the hydrocarbons disclosed herein are characterized by degradation mechanisms that produce few flammable volatiles. For example, 2,4,4′,6-tetrahydroxydeoxybenzoin is employed as a multifunctional cross-linker in conjunction with bis-epoxydeoxybenzoin, affording new resins that combine excellent physical and mechanical properties with low flammability.
Multifunctional deoxybenzoin-based epoxies: Synthesis, mechanical properties, and thermal evaluation
Szyndler, Megan W.,Timmons, Justin C.,Yang, Zhan H.,Lesser, Alan J.,Emrick, Todd
, p. 4441 - 4446 (2014/10/15)
We describe 2,4,4′,6-tetrahydroxydeoxybenzoin (THDB) as a multifunctional cross-linker in conjunction with bis-epoxydeoxybenzoin (BEDB), affording new resins that combine excellent physical and mechanical properties with low flammability. The char residue and heat release capacity values of the cross-linked epoxies were measured by thermogravimetric analysis (TGA) and pyrolysis combustion flow calorimetry (PCFC), respectively. Resins fabricated from THDB exhibited low total heat release (13 kJ/g) and high char yields (34%), as well as good mechanical properties, making them suitable candidates for consideration in high performance adhesive applications. The desirable heat release and char yield properties of these structures are realized without the presence of any conventional flame retardant, such as halogenated structures or inorganic fillers that are commonly utilized in commercial materials.
