156052-68-5

Basic information

• Product Name: ZOXAMIDE
• Synonyms: ZOXAMIDE;rh-7281;zoxamide (bsi,iso);Zoxamid;Zoxamide Solution, 100ppm;Zoxamide Solution, 1000ppm
• CAS NO: 156052-68-5
• Molecular Formula: C₁₄H₁₆Cl₃NO₂
• Molecular Weight: 336.64
• Mol File: 156052-68-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 158-160°; mp 159.5-160.5° (Egan)
• Boiling Point: 415.4°Cat760mmHg
• Flash Point: 205°C
• Appearance: /
• Density: 1.289g/cm³
• Vapor Pressure: 4.13E-07mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: 0-6°C
• PKA: 11.20±0.46(Predicted)
• BRN: 11413911
• CAS DataBase Reference: ZOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: ZOXAMIDE(156052-68-5)
• EPA Substance Registry System: ZOXAMIDE(156052-68-5)

Safety Data

• Hazard Codes: Xi,N
• Statements: 43-50/53
• Safety Statements: 24-37-46-60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 156052-68-5(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 156052-68-5 differently. You can refer to the following data:
1. Zoxamide is a fungacide for control of mildew and late bight. Zoxamide was developped for foliar use on potatoes, vines, and vegetables. Zoxamide is able to specifically target Oomycete fungi; Zoxamid e exhibits strong preventive activity combined with excellent rainfast and residual properties.
2. Agricultural fungicide.
3. Zoxamide is a fungacide for control of mildew and late bight. Zoxamide was developped for foliar use on potatoes, vines, and vegetables. Zoxamide is able to specifically target Oomycete fungi; Zoxamide exhibits strong preventive activity combined with excellent rainfast and residual properties.

Hazard

Low toxicity by ingestion, inhalation, and skin contact.

InChI:InChI=1/C14H16Cl3NO2/c1-4-14(3,12(19)7-15)18-13(20)9-5-10(16)8(2)11(17)6-9/h5-6H,4,7H2,1-3H3,(H,18,20)

Upstream product

• 39652-34-1 3,5-dichloro-4-methylbenzoic acid 
• 113485-46-4 3,5-dichloro-4-methylbenzoyl chloride 
• 209809-70-1 2-(3,5-dichloro-4-methylphenyl)-4-ethyl-4-methyl-5-methyleneoxazoline 
• 87-90-1 trichloroisocyanuric acid 

Downstream Products

• 160171-18-6 (+)-S-zoxamide 
• 160171-18-6 (-)-R-zoxamide 

Relevant articles and documents

Method for preparing benzamide compound

The invention provides a method for preparing a benzamide compound, and belongs to the technical field of organic synthesis. The method for preparing a benzamide compound provided by the invention comprises the following steps: mixing aryl-substituted dihydrooxazole, an acidic catalyst, water and a reaction solvent, and carrying out hydrolysis ring-opening reaction to obtain the benzamide compound, wherein the acidic catalyst is p-toluenesulfonic acid or sulfonic acid ion exchange resin. According to the invention, p-toluenesulfonic acid or sulfonic acid ion exchange resin is used as an acidiccatalyst, under the catalytic action of the p-toluenesulfonic acid or sulfonic acid ion exchange resin, aryl-substituted dihydrooxazole is subjected to hydrolysis ring-opening reaction to obtain thebenzamide compound, only metered toluenesulfonic acid or sulfonic acid ion exchange resin needs to be catalyzed, the toluenesulfonic acid or sulfonic acid ion exchange resin is convenient to remove after the reaction is completed, almost no waste is generated, and industrial production is convenient to achieve.

Method for controlling resistant fungi

A method for controlling phytopathogenic fungi is disclosed. The method uses a fungicidal composition which has been found to be effective against strains of fungi which are resistant to benzimidazole fungicides. When combined with one or more of benzimidazole, thiophanate, or dicarboximide fungicides, and applied to a mixed population of sensitive and resistant fungi, the fungicidal compound of the present invention is more effective against the mixed population of fungi than either of the fungicidal compounds alone.

Development of a process for triazine-promoted amidation of carboxylic acids

A process has been developed for the triazine-promoted amidation of carboxylic acids. We have identified 2,4,6-trichloro-1,3,5-triazine (cyanuric chloride) as a cost-effective reagent for this transformation. The procedure is a suitable alternative to traditional amidation processes when an acid chloride cannot be prepared from the corresponding carboxylic acid due to safety, stability, or handling concerns.