15656-90-3

Basic information

• Product Name: α,α-di-tert-butylbenzyl alcohol
• Synonyms: α,α-di-tert-butylbenzyl alcohol
• CAS NO: 15656-90-3
• Molecular Weight: 220.355
• Mol File: 15656-90-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: α,α-di-tert-butylbenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-di-tert-butylbenzyl alcohol(15656-90-3)
• EPA Substance Registry System: α,α-di-tert-butylbenzyl alcohol(15656-90-3)

Safety Data

• Hazardous Substances Data: 15656-90-3(Hazardous Substances Data)

Upstream product

• 938-16-9 2,2-dimethylpropiophenone 
• 677-22-5 tert-butylmagnesium chloride 
• 815-24-7 Di-t-butyl ketone 
• 591-51-5 phenyllithium 
• 7789-45-9 copper(ll) bromide 
• 75501-40-5 3-Benzyl-2,2,4,4-tetramethyl-3-pentanol 
• 100-58-3 phenylmagnesium bromide 
• 108-86-1 bromobenzene 
• 507-20-0 tertiary butyl chloride 
• 93-89-0 benzoic acid ethyl ester 
• 594-19-4 tert.-butyl lithium 

Downstream Products

• 17603-18-8 2,3-dimethyl-butan-2-yl 
• 16804-70-9 cumyl cation 
• 769-57-3 α,β,β-trimethylstyrene 

Relevant articles and documents

Synthesis and Reactions of 3d Metal Complexes with the Bulky Alkoxide Ligand [OCtBu2Ph]

Treatment of NiCl2(dme) and NiBr2(dme) (dme = dimethoxyethane) with 2 equiv of LiOR (OR = OCtBu2Ph) forms the distorted trigonal planar complexes [NiLiX(OR)2(THF)2] (THF = tetrahydrofuran)

The retro Grignard addition reaction revisited: The reversible addition of benzyl reagents to ketones

The Grignard addition reaction is known to be a reversible process with allylic reagents, but so far the reversibility has not been demonstrated with other alkylmagnesium halides. By using crossover experiments it has been established that the benzyl addition reaction is also a reversible transformation. The retro benzyl reaction was shown by the addition of benzylmagnesium chloride to di-tert-butyl ketone followed by exchange of both the benzyl and the ketone moiety with another substrate. Similar experiments were performed with phenylmagnesium bromide and tert-butylmagnesium chloride, but in these two cases the Grignard addition reaction did not show any sign of a reverse transformation.