1575-95-7Relevant articles and documents
A novel one-pot synthesis of unsymmetrical acyclic imides
Habibi, Zohreh,Salehi, Peyman,Zolfigol, Mohammad Ali,Yousefi, Maryam
, p. 812 - 814 (2007)
A new and convenient method was found for the one-pot synthesis of symmetrical and unsymmetrical linear imides by reaction of aliphatic and aromatic nitriles with acyclic carboxylic anhydrides in the presence of silica sulfuric acid as an active and recyclable reagent. Georg Thieme Verlag Stuttgart.
A solvent effect that influences the preparative utility of N- (silylalkyl)phthalimide and N-(silylalkyl)maleimide photochemistry
Yoon, Ung Chan,Oh, Sun Wha,Lee, Soo Min,Cho, Sung Ju,Gamlin, Janet,Mariano, Patrick S.
, p. 4411 - 4418 (1999)
The photochemistry of selected N-silylalkyl-substituted phthalimides and maleimides has been investigated with the aim of exploring the generality and preparative consequences of an intriguing solvent effect on excited-state reaction chemoselectivities and quantum efficiencies. An example of this effect is found in the photochemistry of N- [(trimethylsilyl)butyl]phthalimide 10, where irradiation in MeCN leads to production of a mixture of four products that arise by excited-state intramolecular hydrogen-atom abstraction. In contrast, the benzoindolizidine 15 is the sole product produced by a single electron transfer (SET)- desilylation pathway upon irradiation of 10 in 35% H2O-MeCN. Another example of this solvent effect is found in the photochemistry of the N-silylpropyl- maleimide 17. Irradiation in MeCN results in the production of the 2+2-dimer 19 whereas the pyrrolizidine 18 is generated exclusively by irradiation of 17 in 35% H2O-MeCN. The results of fluorescence and triplet sensitization experiments suggest that the solvent effect has multiple sources including the control of the nature, reactivity, and intrinsic lifetimes of singlet and triplet excited states of the phthalimide and maleimide systems. The exploratory studies have clearly demonstrated the generality of this solvent effect and how it can be used to enhance the preparative utility of the photochemistry of N-(silylalkyl)phthalimides and N-(silylalkyl)maleimides.
Method for preparing derivatives of benzamide under microwave condition in aqueous phase
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Paragraph 0019; 0068, (2019/03/28)
The invention discloses a method for preparing derivatives of benzamide under a microwave condition in an aqueous phase. A coupling reaction is carried out between substituted benzoic acid and amine under the microwave condition in the aqueous phase. The method for preparing the derivatives of benzamide is environmentally friendly, easy and convenient to operate, safe, low in cost and efficient. Compared with the prior art, the method can be applicable to a large number of functional groups, is high in yield, produces fewer by-products, and further is easy to operate, safe, low in cost and environmentally friendly. A formula is shown in the description.
Palladium-Catalyzed Solvent-Controlled Selective Synthesis of Acyl Isoureas and Imides from Amides, Isocyanides, Alcohols and Carboxylates
Cao, Ming,Liu, Liqiu,Tang, Shi,Peng, Zhiyuan,Wang, Yingchun
supporting information, p. 1887 - 1895 (2019/03/11)
A highly selective synthesis of acyl isoureas and imides from readily accessible amides, isocyanides, alcohols and carboxylates based on reaction solvent selection is described. In the presence of a catalytic amount of [1,1′-bis(diphenylphosphino)ferrocene]dichloropalladium(II) and cupric acetate, treatment of amides and isocyanides in alcohols at 60 °C provided acyl isoureas in high yields. Interestingly, when other solvents such as acetonitrile was used instead of alcohols, imides were exclusively produced in good to excellent yields via direct N-acylation of amides with carboxylates as the acyl sources. This protocol offers an attractive alternative approach toward isoureas and imides. (Figure presented.).
A carbonylation reaction of carbon monoxide in the method of preparing amide
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Paragraph 0024; 0025; 0026; 0027; 0028-0032; 0131-0132; 0147, (2018/07/30)
The invention belongs to the technical field of synthesis of amides, discloses a process for the carbonylation of carbon monoxide in the method of preparing amide, the method is to cheap and easy to obtain the halogenated aromatic hydrocarbon and organic amine compounds as the substrate of reaction, to carbon monoxide as carbonyl source, under light-struck, halogenated aromatic hydrocarbons are cracked to produce free radical, by free-radical addition process to obtain the amide compound. Compared with the traditional carbonylation reaction, the carbon monoxide pressure is extremely low, can react to the atmospheric pressure. This process does not need to rely on any metal catalyst of the booster, mild reaction conditions, environmental protection, with a shorter synthetic route and high utilization efficiency of the atoms, the reaction system with higher substrate tolerance, green sustainable light source as the driving force, the atom economy is high, application prospect.
