158817-11-9 Usage
General Description
FMOC-TYR(PO3(MDPSE)2)-OH is a chemical compound commonly used in peptide synthesis and modification. It consists of a tyrosine amino acid modified with two phosphoryl methyl diselenide (MDPSE) groups and a FMOC (9-fluorenylmethoxycarbonyl) protecting group at the amino terminus. The phosphoryl groups confer negative charges and can participate in phosphorylation reactions, making this compound useful for studying the role of phosphorylation in biological processes. The FMOC group serves as a protecting group to prevent unwanted reactions during peptide synthesis. Overall, FMOC-TYR(PO3(MDPSE)2)-OH is a versatile and important chemical for studying and developing peptides with specific biological functions.
Check Digit Verification of cas no
The CAS Registry Mumber 158817-11-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,8,1 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 158817-11:
(8*1)+(7*5)+(6*8)+(5*8)+(4*1)+(3*7)+(2*1)+(1*1)=159
159 % 10 = 9
So 158817-11-9 is a valid CAS Registry Number.
158817-11-9Relevant articles and documents
Synthesis and Application of Bis-Silylethyl-Derived Phosphate-Protected Fmoc-Phosphotyrosine Derivatives for Peptide Synthesis
Chao, Hann-Guang,Bernatowicz, Michael S.,Reiss, Paul D.,Matsueda, Gary R.
, p. 6687 - 6691 (2007/10/02)
Three Fmoc-phosphotyrosine derivatives with silylethyl-based phosphate protection were synthesized and evaluated for use in peptide synthesis.The stability of these derivatives toward piperidine/DMF (1:4) treatment and their cleavability with TFA solutions were examined.On the basis of these data, the bis-protected Fmoc-phosphotyrosine derivative or Fmoc-Tyr(PO3MDPSE2)-OH, was shown to be the most suitable candidate for the production of phosphotyrosine peptides.The syntheses of phosphotyrosine peptides including one containing Met and Cys are described.
