160823-58-5

Basic information

• Product Name: (5R,6S,7R)-5-Hydroxy-5-(3,4,5-trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6,7-dicarboxylic acid bis-((S)-methoxycarbonyl-phenyl-methyl) ester
• Synonyms: (5R,6S,7R)-5-Hydroxy-5-(3,4,5-trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6,7-dicarboxylic acid bis-((S)-methoxycarbonyl-phenyl-methyl) ester
• CAS NO: 160823-58-5
• Molecular Weight: 742.733
• Mol File: 160823-58-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5R,6S,7R)-5-Hydroxy-5-(3,4,5-trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6,7-dicarboxylic acid bis-((S)-methoxycarbonyl-phenyl-methyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: (5R,6S,7R)-5-Hydroxy-5-(3,4,5-trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6,7-dicarboxylic acid bis-((S)-methoxycarbonyl-phenyl-methyl) ester(160823-58-5)
• EPA Substance Registry System: (5R,6S,7R)-5-Hydroxy-5-(3,4,5-trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6,7-dicarboxylic acid bis-((S)-methoxycarbonyl-phenyl-methyl) ester(160823-58-5)

Safety Data

• Hazardous Substances Data: 160823-58-5(Hazardous Substances Data)

Upstream product

• 134454-88-9 1-(3',4',5'-trimethoxyphenyl)-1,2-dihydro-4,5-methylenedioxybenzocyclobuten-1-ol 
• 138380-77-5 Fumarate of (S)-Methyl mandelate 
• 68415-05-4 α-(3,4,5-trimethoxyphenyl)-α-morpholinoacetonitrile 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 134454-84-5 1-(3,4,5-trimethoxyphenyl)-2-(2'-iodo-4',5'-methylenedioxyphenyl)ethanone 

Downstream Products

• 477-51-0 deoxypodophyllotoxin 
• 160823-61-0 (5R,6R,7R)-5-(3,4,5-Trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6,7-dicarboxylic acid 
• 160869-33-0 (5R,5aR,8aR)-5-(3,4,5-Trimethoxy-phenyl)-5,5a,8a,9-tetrahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxole-6,8-dione 
• 160823-59-6 (5R,6R,7R)-5-(3,4,5-Trimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxole-6,7-dicarboxylic acid bis-((S)-methoxycarbonyl-phenyl-methyl) ester 

Relevant articles and documents

An asymmetric synthesis of (-)-deoxypodophyllotoxin

A Diels-Alder cycloaddition between the fumarate of methyl (S)-mandelate (22) and α-hydroxy-α-aryl-o-quinodimethane 21 produces an endo cycloadduct (23) in 58% yield. The preparation of the precursor to o-quinodimethane 21 and the conversion of cycloadduct 23 to optically pure (-)-deoxypodophyllotoxin (1) is described.