161201-03-2

Basic information

• Product Name: dimethyl N-<4-<<(2,4-diaminoquinazolin-5-yl)methyl>amino>benzoyl>-L-glutamate
• Synonyms: dimethyl N-<4-<<(2,4-diaminoquinazolin-5-yl)methyl>amino>benzoyl>-L-glutamate
• CAS NO: 161201-03-2
• Molecular Weight: 466.497
• Mol File: 161201-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl N-<4-<<(2,4-diaminoquinazolin-5-yl)methyl>amino>benzoyl>-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl N-<4-<<(2,4-diaminoquinazolin-5-yl)methyl>amino>benzoyl>-L-glutamate(161201-03-2)
• EPA Substance Registry System: dimethyl N-<4-<<(2,4-diaminoquinazolin-5-yl)methyl>amino>benzoyl>-L-glutamate(161201-03-2)

Safety Data

• Hazardous Substances Data: 161201-03-2(Hazardous Substances Data)

Upstream product

• 52407-60-0 dimethyl N-(4-amino-benzoyl)-L-glutamate 
• 137553-45-8 2,4-diaminoquinazoline-5-carbonitrile 

Relevant articles and documents

2,4-Diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii

2,4-Diaminoquinazoline antifolates with a lipophilic side chain at the 5- position, and in one case with a classical (p-aminobenzoyl)-L-glutamate side chain, were synthesized as potentially selective inhibitors of a site- directed mutant of human dihydrof