1616074-91-9

Basic information

• Product Name: N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-methyl-2-phenoxypropanamide
• Synonyms: N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-methyl-2-phenoxypropanamide
• CAS NO: 1616074-91-9
• Molecular Weight: 368.476
• Mol File: 1616074-91-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-methyl-2-phenoxypropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-methyl-2-phenoxypropanamide(1616074-91-9)
• EPA Substance Registry System: N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-methyl-2-phenoxypropanamide(1616074-91-9)

Safety Data

• Hazardous Substances Data: 1616074-91-9(Hazardous Substances Data)

Upstream product

• 943-45-3 2-methyl-2-phenoxypropionic acid 
• 954279-15-3 1-amino-3-(3,4-dihydroisoquinoline-2(1H)-yl)propan-2-ol 
• 18672-04-3 ethyl 2-methyl-2-phenoxypropanoate 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 108-95-2 phenol 
• 140406-65-1 2-(oxiran-2-ylmethyl)-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF

Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5- mediated disorders are also described.