1620100-87-9

Basic information

• Product Name: 8-((4-methylphenyl)sulfonamido)-quinoline N-oxide
• Synonyms: 8-((4-methylphenyl)sulfonamido)-quinoline N-oxide
• CAS NO: 1620100-87-9
• Molecular Weight: 314.365
• Mol File: 1620100-87-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 8-((4-methylphenyl)sulfonamido)-quinoline N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 8-((4-methylphenyl)sulfonamido)-quinoline N-oxide(1620100-87-9)
• EPA Substance Registry System: 8-((4-methylphenyl)sulfonamido)-quinoline N-oxide(1620100-87-9)

Safety Data

• Hazardous Substances Data: 1620100-87-9(Hazardous Substances Data)

Upstream product

• 91-22-5 quinoline 
• 98-59-9 p-toluenesulfonyl chloride 
• 1613-37-2 Quinoline N-oxide 
• 941-55-9 4-toluenesulfonyl azide 

Downstream Products

• 92339-84-9 8-aminoquinoline-1-oxide 
• 10304-39-9 4-methyl-N-quinolin-8-yl-benzenesulfonamide 
• 15011-25-3 CU-225 

Relevant articles and documents

Novel Production Method for Aminated Azine

[4] The present invention relates to a novel process for the preparation of bicyclic continuous ring compounds. To the present invention, the novel reactivity of acetal utilized as a unit structure for protecting an existing carbonyl group or hydroxyl gro

Rh(III)-Catalyzed C(8)-H Activation of Quinoline N-Oxides: Regioselective C-Br and C-N Bond Formation

A highly efficient and regioselective Rh(III)-catalyzed protocol for C8-bromination and amidation of quinoline N-oxide was developed. The transformation was found to be successful up to gram scale with excellent functional group tolerance and wide substrate scope. The mechanistic study revealed five-membered rhodacycle with quinoline N-oxide as a key intermediate for regioselective C8-functionalization. In addition, NFSI (N-fluorobis(phenylsulfonyl)-imide) was explored as an amidating reagent for C8-amidation of quinoline N-oxide for the first time.

Recent developments in the chemistry of heteroaromatic N -oxides

Selected developments in the chemistry of heteroaromatic N-oxides since 2001 are presented in this review. The use of these N-oxides, both in late-transition-metal-catalyzed oxidations of carbon-carbon triple bonds and in regioselective C-H functionalizations of the heteroarene, are contemporary topics of interest and the focus of the discussion. 1 Introduction 2 Synthesis of Heteroaromatic N-Oxides 2.1 Direct Oxidation of Hindered Heteroarenes 2.2 Through Construction of Heteroaromatic Rings 3 Heteroaromatic N-Oxides as Oxidants 3.1 Alkyne Oxidation 3.2 Allene Oxidation 3.3 Carbene Oxidation 4 Heteroaromatic N-Oxides as Substrates 4.1 Deoxygenative ortho-C-H Functionalization with Prior Activation 4.2 Deoxygenative ortho-C-H Functionalization with Nonstabilized Carbanions 4.3 Nondeoxygenative C-H Functionalization 4.3.1 ortho-C-H Functionalization 4.3.2 N-Oxide Directed ortho-Alkyl C-H Functionalization 4.3.3 N-Oxide Directed Remote C-H Functionalization 4.4 1,3-Dipolar Cycloaddition 5 Conclusion and Outlook.