1627962-88-2Relevant articles and documents
Synthesis of novel hexahydroquinolines and 6-amino-2-oxopyridine-3,5-dicarbonitriles incorporating sulfamethoxazole via [3?+?3] annulation
Abdelmoniem, Amr M.,Abdelrahman, Mohamed Gamal Mohamed,Ghozlan, Said Ahmed Soliman,Abdelhamid, Ismail A.
, p. 3387 - 3395 (2019/11/03)
Cyclic enaminone and cyanoacetamide derivative with incorporated sulfamethoxazole moiety were prepared. Their reactions with arylidenemalononitrile derivatives in ethanol or pyridine/piperidine at reflux yielded the corresponding hexahydroquinoline and 6-amino-2-oxopyridine-3,5-dicarbonitrile derivatives incorporating sulfamethoxazole. The mechanism and structural elucidation of products were discussed.