1638760-80-1 Usage
General Description
Methyl oxetane-3-carboxylate, also known as methyl 3-oxetanecarboxylate, is a chemical compound with the molecular formula C5H8O3. It is a cyclic ester derivative of oxetane and is commonly used as a building block in organic synthesis. Methyl oxetane-3-carboxylate is known for its potential use in the pharmaceutical industry for the synthesis of various biologically active compounds. It also has applications in the production of agrochemicals and materials science. The compound has attracted interest for its unique structure and reactivity, making it a valuable intermediate in the synthesis of complex molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 1638760-80-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,3,8,7,6 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1638760-80:
(9*1)+(8*6)+(7*3)+(6*8)+(5*7)+(4*6)+(3*0)+(2*8)+(1*0)=201
201 % 10 = 1
So 1638760-80-1 is a valid CAS Registry Number.
1638760-80-1Relevant articles and documents
Synthesis of oxetane-3-carboxaldehyde and methyl oxetane-3-carboxylate via homologation of oxetane-3-one
Kephart, Susan E.,Zehnder, Luke R.,Huang, Buwen,Sutton, Scott C.
, p. 3641 - 3646 (2016)
A 4-pot telescoped procedure to prepare oxetane-3-carboxaldehyde and methyl oxetane-3-carboxylate was developed using readily available starting materials. Classical homologation methods applied to oxetane-3-one proved challenging due to the sensitivity of the oxetane ring toward strongly oxidative, basic and acidic conditions. Subsequently, a mild homologation sequence was developed. The key steps involve a Tsuji hydrogenolysis of an allylic acetate, osmium-free dihydroxylation and oxidative cleavage. Although methyl oxetane-3-carboxylate is marketed by a small number of specialty chemical companies, this work represents the first published preparation of this vital building block.