1647060-94-3

Basic information

• Product Name: (S)-4-benzyl-N-[(S)-5-methoxy-5-oxo-2-(1-(2,2,6,6-tetramethylpiperidinyl)oxy)pentanoyl]-5,5-dimethyl-1,3-oxazolidin-2-one
• CAS NO: 1647060-94-3
• Molecular Weight: 488.624
• Mol File: 1647060-94-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-benzyl-N-[(S)-5-methoxy-5-oxo-2-(1-(2,2,6,6-tetramethylpiperidinyl)oxy)pentanoyl]-5,5-dimethyl-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-benzyl-N-[(S)-5-methoxy-5-oxo-2-(1-(2,2,6,6-tetramethylpiperidinyl)oxy)pentanoyl]-5,5-dimethyl-1,3-oxazolidin-2-one(1647060-94-3)
• EPA Substance Registry System: (S)-4-benzyl-N-[(S)-5-methoxy-5-oxo-2-(1-(2,2,6,6-tetramethylpiperidinyl)oxy)pentanoyl]-5,5-dimethyl-1,3-oxazolidin-2-one(1647060-94-3)

Safety Data

• Hazardous Substances Data: 1647060-94-3(Hazardous Substances Data)

Upstream product

• 168297-85-6 (S)-4-benzyl-5,5-dimethyloxazolidin-2-one 
• 1647060-93-2 (S)-4-benzyl-5,5-dimethyl-N-[(S)-3-phenyl-2-(1-(2,2,6,6-tetramethylpiperidinyl)oxy)-propanoyl]-1,3-oxazolidin-2-one 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 
• 2564-83-2 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical 
• 1647060-89-6 (S)-4-benzyl-N-(5-methoxy-5-oxopentanoyl)-5,5-dimethyl-1,3-oxazolidin-2-one 
• 168297-97-0 (S)-4-benzyl-5,5-dimethyl-N-(3-phenylpropanoyl)-1,3-oxazolidin-2-one 

Relevant articles and documents

Stereoselective aminoxylation of biradical titanium enolates with TEMPO

A highly efficient and straightforward aminoxylation of titanium(IV) enolates from (S)-N-acyl-4-benzyl-5,5-dimethyl-1,3-oxazolidin-2-ones with TEMPO has been developed. A wide array of functional groups on the acyl moiety, including alkyl and aryl substituents, olefins, esters, or α-cyclopropyl, as well as α-trifluoromethyl groups, are well tolerated. This transformation can therefore produce the α-aminoxylated adducts in excellent yields with high diastereomeric ratios (d.r.). In turn, parallel additions to the α,β-unsaturated N-acyl counterparts give the corresponding γ-adducts with complete regioselectivity in moderate to good yields. Removal of the piperidinyl moiety or the chiral auxiliary converts the resultant adducts into enantiomerically pure α-hydroxy carboxyl derivatives, alcohols, or esters in high yields under mild conditions. Finally, a new mechanistic model based on the biradical character of the titanium(IV) enolates has been proposed.