168134-59-6Relevant articles and documents
An improved synthesis and resolution of (±)-cis,cis-2,2'-spirobiindane-1,1'-diol
Nieman,Keay
, p. 1575 - 1583 (1995)
(±)-cis,cis-2,2'-spirobiindane-1,1'-diol (1) is synthesized stereoselectively in four steps beginning with 1-indanone in 68% overall yield. An improved resolution of diol 1 is described by preparing and separating diastereomeric mono-esters of 1 using (2S)-O-(tert-butyldimethylsilyl)mandeloyl chloride (10).