61895-27-0

Basic information

• Product Name: (+)-2,2'-Spirobiindan-1,1'-dion
• CAS NO: 61895-27-0
• Molecular Weight: 248.281
• Mol File: 61895-27-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: (+)-2,2'-Spirobiindan-1,1'-dion(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-2,2'-Spirobiindan-1,1'-dion(61895-27-0)
• EPA Substance Registry System: (+)-2,2'-Spirobiindan-1,1'-dion(61895-27-0)

Safety Data

• Hazardous Substances Data: 61895-27-0(Hazardous Substances Data)

Upstream product

• 4372-32-1 dibenzylmalonic acid 
• 100-44-7 benzyl chloride 
• 61895-27-0 2,2'-spirobiindan-1,1'-dione 
• 40932-28-3 dibenzylmalonyl Dichloride 
• 28977-42-6 2-((1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)benzoic acid 
• 56174-55-1 C₂₇H₂₆O₅ 
• 40932-30-7 2,2'-Spirobiindan-1-on 
• 412010-78-7 2-((1-oxo-1,3-dihydro-2H-inden-2-ylidene)methyl)benzoic acid 
• 1380601-37-5 2-methoxycarbonyl-2-(2-(ethoxycarbonyl)phenylmethyl)-1-indanone 
• 125868-06-6 ethyl 2-benzyl-1-indanone-2-carboxylate 
• 52421-82-6 Dibenzylmalonsaeure-monoaethylester 
• 53082-74-9 dibenzyl-malonic acid ethyl ester chloride 
• 37558-41-1 2-Benzyl-2-(2-ethoxycarbonyl-benzyl)-malonic acid diethyl ester 
• 37558-42-2 Benzyl-o-carboxybenzylmalonsaeure 

Downstream Products

• 28977-42-6 2-((1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)benzoic acid 
• 37558-43-3 (+)-2,2'-Spirobiindan-1,1'-dion 
• 37558-43-3 (-)-(2R)-2,2'-spirobiindan-1,1'-dione 
• 243-17-4 2,3-benzofluorene 
• 860756-40-7 1'-benzyl-1-hydroxy-2,2'-spirobiindan-1-one 
• 859961-22-1 1,1'-dibenzyl-2,2'-spirobiindane-1,1'-diol 
• 252190-44-6 2-[(1,3-dioxo-indan-2-ylidene)-hydroxy-methyl]-benzoic acid ethyl ester 
• 606-23-5 1H-indene-1,3(2H)-dione 
• 846589-71-7 2-[3-(2-formylphenyl)-2-oxopropyl]benzoic acid 
• 846589-69-3 2-(1H-inden-2-ylmethyl)benzoic acid 
• 168134-62-1 (1S,1'S,2S)-2,2'-spirobiindan-1-((2S)-(O-tert-butyldimethylsilyl)mandeloxy)-1'-ol 
• 168254-22-6 (1R,2R,1'R)-2,2'-spirobiindan-1-((2S)-(O-tert-butyldimethylsilyl)mandeloxy)-1'-ol 
• 37558-43-3 (+)-(2S)-2,2'-spirobiindane-1,1'-dione 

Relevant articles and documents

Catalytic enantioselective synthesis of chiral spirocyclic 1,3-diketones: Via organo-cation catalysis

An SPA-triazolium bromide-catalyzed transannular C-acylation of enol lactones is presented. This methodology provides convenient access to a range of enantioenriched spirocyclic 1,3-diketones in moderate to high yields and enantioselectivities and features a broad substrate scope in terms of enol lactones. The catalytic capability of this triazolium salt catalyst is also demonstrated in this enantioselective transformation, which could inspire its further application. This journal is

Catalytic Enantioselective Synthesis of C1- and C2-Symmetric Spirobiindanones through Counterion-Directed Enolate C-Acylation

A catalytic enantioselective route to C1- and C2-symmetric 2,2′-spirobiindanones has been realized through an intramolecular enolate C-acylation. This reaction employs a chiral ammonium counterion to direct the acylation of an in situ generated ketone enolate with a pentafluorophenyl ester. This reaction constitutes the first example of a direct catalytic enantioselective C-acylation of a ketone and provides an efficient and highly enantioselective route to axially chiral spirobiindanediones. These products can be diastereoselectively derivatized, offering access to a range of functionalized spirocyclic architectures.

Exciton chirality method in vibrational circular dichroism

The interaction of two IR chromophores yields a strong vibrational circular dichroism couplet whose sign reflects the absolute configuration of the molecule. We present a method to determine absolute configuration of a chiral molecule based on this couplet without need of theoretical calculation. Not only can this method analyze various molecules whose absolute configuration is difficult to determine by other spectroscopic methods, but also it can significantly enhance VCD signals.