168263-82-9

Basic information

• Product Name: (2S,4S)-4-BOC-AMINO PYRROLIDINE-2-CARBOXYLIC ACID METHYLESTER-HCL
• Synonyms: (2S,4S)-4-BOC-AMINO PYRROLIDINE-2-CARBOXYLIC ACID METHYLESTER-HCL;4-N-BOC-4(S)-AMINO-PYRROLIDINE-2(S)-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE;(2S,4S)-4-Boc-Aminopyrrolidine-2-carboxylic acid methyl ester hydrochloride;(2S,4S)-methyl 4-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate;(4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-L-Proline methyl ester;cis-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-L-Proline methyl ester;Methyl (2S,4S)-4-Boc-aMinopyrrolidine-2-carboxylate hydrochloride;Methyl (2S,4S)-4-(tert-butoxycarbonylaMino)pyrrolidine-2-carboxylate hydrochloride
• CAS NO: 168263-82-9
• Molecular Formula: C₁₁H₂₀N₂O₄
• Molecular Weight: 280.7484
• Mol File: 168263-82-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 347.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.13±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 11.90±0.40(Predicted)
• CAS DataBase Reference: (2S,4S)-4-BOC-AMINO PYRROLIDINE-2-CARBOXYLIC ACID METHYLESTER-HCL(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-4-BOC-AMINO PYRROLIDINE-2-CARBOXYLIC ACID METHYLESTER-HCL(168263-82-9)
• EPA Substance Registry System: (2S,4S)-4-BOC-AMINO PYRROLIDINE-2-CARBOXYLIC ACID METHYLESTER-HCL(168263-82-9)

Safety Data

• Hazardous Substances Data: 168263-82-9(Hazardous Substances Data)

Usage

General Description

"(2S,4S)-4-BOC-AMINO PYRROLIDINE-2-CARBOXYLIC ACID METHYLESTER-HCL", also known as (S)-tert-Butoxycarbonyl-4-amino-2-pyrrolidinecarboxylic acid methyl ester hydrochloride, is a complex organo-chemical compound. It consists of several functional groups including an amino group, a pyrrolidine ring, a carboxylic acid group which is esterified with methanol, and a BOC(tert-Butoxycarbonyl) group that serves as a protecting group for the amino function. Lastly, the HCL refers to its hydrochloride salt form which enhances its stability. This chemical is primarily utilized in the field of pharmaceuticals and medicines, largely serving as an intermediate in the synthesis of more complex active pharmaceutical ingredients (APIs).

InChI:InChI=1/C11H20N2O4.ClH/c1-11(2,3)17-10(15)13-7-5-8(12-6-7)9(14)16-4;/h7-8,12H,5-6H2,1-4H3,(H,13,15);1H/t7-,8-;/m0./s1

Upstream product

• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 51-35-4 4R-4-hydroxyproline 
• 117811-78-6 methyl (2S,4R)-1-benzyloxycarbonyl-4-methanesulfonyloxypyrrolidine-2-carboxylate 
• 113490-74-7 4(S)-azido-N-<(phenylmethoxy)carbonyl>-(S)-proline methyl ester 
• 64187-48-0 methyl (2S,4R)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylate 
• 168263-80-7 methyl (2S,4S)-1-benzyloxycarbonyl-4-tert-butoxycarbonylaminopyrrolidine-2-carboxylate 

Downstream Products

• 221352-74-5 (2S,4S)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine2-carboxylic acid 
• 168263-80-7 methyl (2S,4S)-1-benzyloxycarbonyl-4-tert-butoxycarbonylaminopyrrolidine-2-carboxylate 

Relevant articles and documents

THIENOPYRAZOLE DERIVATIVE HAVING PDE7 INHIBITORY ACTIVITY

To provide thienopyrazole derivatives inhibiting PDE 7 selectively, and therefore, enhance cellular cAMP level. Consequently, the compound is useful for treating various kinds of disease such as allergic diseases, inflammatory diseases or immunologic diseases. The compound is thienopyrazole compound represented by the following formula (I): [wherein, especially, R 1 is a cyclohexyl, a cycloheptyl group or a tetrahydropyranyl group; R 2 is methyl; R 3 is a hydrogen atom; and R 4 is a group: -CONR 5 R 6 (in which any one of R 5 and R 6 is a hydrogen atom)].