171046-49-4

Basic information

• Product Name: (-)-5(S)-(3-methoxybenzyl)-1-cyclopentenecarboxylic acid
• CAS NO: 171046-49-4
• Molecular Weight: 232.279
• Mol File: 171046-49-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (-)-5(S)-(3-methoxybenzyl)-1-cyclopentenecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-5(S)-(3-methoxybenzyl)-1-cyclopentenecarboxylic acid(171046-49-4)
• EPA Substance Registry System: (-)-5(S)-(3-methoxybenzyl)-1-cyclopentenecarboxylic acid(171046-49-4)

Safety Data

• Hazardous Substances Data: 171046-49-4(Hazardous Substances Data)

Upstream product

• 824-98-6 m-methoxybenzyl chloride 
• 143168-16-5 ethyl (R)-5-acetoxycyclopent-1-enecarboxylate 
• 171046-47-2 (-)-ethyl 5(S)-(3-methoxybenzyl)-1-cyclopentencarboxylate 

Downstream Products

• 911676-51-2 3-[(1S,2S)-2-(4,5-Diphenyl-oxazol-2-yl)-cyclopentylmethyl]-phenol 
• 911676-52-3 3-[(1S,2R)-2-(4,5-Diphenyl-oxazol-2-yl)-cyclopentylmethyl]-phenol 
• 911676-49-8 2-[(1S,2S)-2-(3-Methoxy-benzyl)-cyclopentyl]-4,5-diphenyl-oxazole 
• 911676-50-1 2-[(1R,2S)-2-(3-Methoxy-benzyl)-cyclopentyl]-4,5-diphenyl-oxazole 
• 171046-58-5 (+)-(5S)-1-(4,5-diphenyloxazol-2-yl)-5-(3-methoxybenzyl)cyclopentene 
• 171046-88-1 (S)-5-(3-Methoxy-benzyl)-cyclopent-1-enecarbonyl chloride 

Relevant articles and documents

Replacing the cyclohexene-linker of FR181157 leading to novel IP receptor agonists: Orally active prostacyclin mimetics. Part 6

The synthesis and biological activity of novel derivatives of our previously reported IP receptor agonist FR181157 is described. SAR studies to replace the cyclohexene-linker of FR181157 led to the discovery of compound 1i (FR207845) as a potent non-prost