171869-48-0Relevant articles and documents
Synthesis of 7beta-sulfur analogues of paclitaxel utilizing a novel epimerization of the 7alpha-thiol group.
Mastalerz,Zhang,Kadow,Fairchild,Long,Vyas
, p. 1613 - 1615 (2007/10/03)
Paclitaxel analogues with a sulfur group at the 7beta position were required for SAR studies. Attempts to generate these compounds by displacing a 7alpha leaving group with sulfur nucleophiles were unsuccessful. Instead, these compounds were successfully