173435-41-1

Basic information

• Product Name: 3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER
• Synonyms: METHYL 3-AMINO-2-CHLOROISONICOTINATE;3-AMINO-2-CHLORO-4-PYRIDINECARBOXYLIC ACID METHYL ESTER;3-AMINO-2-CHLOROPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER;3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER;3-AMino-2-chloropyridin-4-carboxylic acid Methyl ester;Methyl 3-amino-2-chloropyridine-4-carboxylate, 3-Amino-2-chloro-4-(methoxycarbonyl)pyridine;Methyl 3-aMino-2-chloropyridine-4-carboxylate;3-AMino-2-chlorisonicotinic acid Methyl ester
• CAS NO: 173435-41-1
• Molecular Formula: C7H7ClN2O2
• Molecular Weight: 186.6
• Product Categories: pharmacetical;Amines;Pyridines;Pyridine;API intermediates
• Mol File: 173435-41-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 317.4 °C at 760 mmHg
• Flash Point: 145.7 °C
• Appearance: /
• Density: 1.384
• Vapor Pressure: 0.000386mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 1.12±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER(173435-41-1)
• EPA Substance Registry System: 3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER(173435-41-1)

Safety Data

• Hazardous Substances Data: 173435-41-1(Hazardous Substances Data)

Usage

General Description

3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER is a chemical compound with the molecular formula C7H7ClN2O2. It is a methyl ester derivative of 3-amino-2-chloro-isonicotinic acid, which is commonly used in organic synthesis and pharmaceutical research. 3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER has potential applications in medicinal chemistry, specifically in the development of new drugs and pharmaceutical formulations. It may also be used as a building block in the synthesis of various organic compounds and in the study of chemical reactions. Additionally, its unique structure and properties make it an interesting subject for further investigation in the field of chemical research. Overall, 3-AMINO-2-CHLORO-ISONICOTINIC ACID METHYL ESTER is a versatile chemical compound with potential applications in various fields of science and industry.

InChI:InChI=1/C7H7ClN2O2/c1-12-7(11)4-2-3-10-6(8)5(4)9/h2-3H,9H2,1H3

Upstream product

• 118-52-5 1,3-dichloro-5,5-dimethylhydantoin 
• 55279-30-6 methyl 3-aminoisonicotinate 
• 103698-10-8 methyl 3-nitropyridine-4-carboxylate 

Downstream Products

• 1260663-37-3 4,8-dichloropyrido[3,4-d]pyrimidine 
• 1470249-17-2 2,4,8-trichloropyrido[3,4-d]pyrimidine 
• 1227581-39-6 methyl 3-amino-2-methylisonicotinate 

Relevant articles and documents

HISTONE DEMETHYLASE INHIBITORS

The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyrido[3,4-d]pyrimidin-4-one derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like

N-pyridinyl[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides

Substituted N-pyridinyl[1,2,4]triazolo[1,5-c]-pyrimidine-2-sulfonamide compounds, such as N-(2-fluoro-4-methyl)-7-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide, were prepared bycondensation of a 2-chlorosulfonyl[1,2,4]triazolo[1,5-c]pyrimidine compound, such as 2-chlorosulfonyl-7-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine, with a substituted 3-aminopyridine compound, such as 3-amino-2-fluoro-4-methylpyridine, and found to possess herbicidal utility.

N-pyridinyl[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides

Substituted N-pyridinyl[1,2,4]triazolo[1,5-c]-pyrimidine-2-sulfonamide compounds, such as N-(2-fluoro-4-methyl)-7-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide, were prepared by condensation of a 2-chlorosulfonyl[1,2,4]triazolo[1,5-c]pyrimidine compound, such as 2-chlorosulfonyl-7-fluoro-5-methoxy[1,2,4]triazolo[1,5-c]pyrimidine, with a substituted 3-aminopyridine compound, such as 3-amino-2-fluoro-4-methylpyridine, and found to possess herbicidal utility.